Results 31 to 40 of about 4,888 (207)
The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors
British Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +206 more
wiley +1 more source
Saudi Journal of Kidney Diseases and Transplantation, 2012 We present a female neonate with arthrogryposis, renal tubular abnormalities and cholestasis syndrome and complex renal structural and functional abnormalities that include medul-lary nephrocalcinosis, hydronephrosis, nephrogenic diabetes insipidus ...
Majid Malaki +2 more
doaj +1 more source
Advanced Science, Volume 12, Issue 38, October 13, 2025.Li exposure up‐regulates FOXO1 expression levels and thus promotes FOXO1‐mediated STEAP4 transcription, up‐regulating STEAP4 levels. Subsequently, STEAP4 up‐regulates intracellular Cu+ ion levels and causes cuproptosis, which further induces miscarriage.
Shuaishuai Xing +14 more
wiley +1 more source
Archives of Endocrinology and Metabolism, 2015 Diabetes insipidus is a disease in which large volumes of dilute urine (polyuria) are excreted due to vasopressin (AVP) deficiency [central diabetes insipidus (CDI)] or to AVP resistance (nephrogenic diabetes insipidus).
Giuseppe Murdaca +10 more
doaj +1 more source
Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 688-701, October 2025.ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González +8 more
wiley +1 more source
Prevalence, Risk Factors and Complications of Diabetes Insipidus in the Republic of Uzbekistan
Mìžnarodnij Endokrinologìčnij Žurnal, 2013 Despite the fact that diabetes insipidus (DI) is a rare independent disorder, there are many publications on this subject in the contemporary literature. Interest to the problem of DI is due to the fact that the syndrome of diabetes insipidus can be both
Z.Yu. Khalimova +6 more
doaj +1 more source
BMC Endocrine Disorders, 2021 Background Diabetes insipidus (DI) can be a common cause of polydipsia and polyuria. Here, we present a case of congenital nephrogenic diabetes insipidus (CNDI) accompanied with central diabetes insipidus (CDI) secondary to pituitary surgery.
Wei Zhang +4 more
doaj +1 more source
Mechanisms governing GPCR anterograde transport
FEBS Letters, Volume 599, Issue 17, Page 2420-2438, September 2025.G protein‐coupled receptors (GPCRs) determine human physiology by transducing ligand binding into intracellular signaling. The transport of nascent GPCRs from the endoplasmic reticulum to the cell surface is critical for cellular responsiveness. We discuss mechanisms regulating GPCR trafficking through secretory organelles, retention of disease‐related
Kevin Assoumou +3 more
wiley +1 more source
Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus
Nature Communications, 2017 Nrf2 regulates oxidative and electrophilic stress responses by modulating the expression of enzymes involved in detoxification pathways. Here Suzukiet al.
Takafumi Suzuki +9 more
doaj +1 more source
Physiological basis of arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP-resistance (AVP-R, formerly nephrogenic diabetes insipidus) [PDF]
Exploration of MedicineThis review explored the physiological mechanisms underlying arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP resistance (AVP-R, formerly nephrogenic diabetes insipidus), with a focus on water balance regulation. Vital
Osah Martins Onwuka
doaj +1 more source