Results 31 to 40 of about 3,546 (164)

Lithium Exposure Causes Trophoblast Cuproptosis by Upregulating FOXO1/STEAP4 Axis in Unexplained Miscarriage

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Li exposure up‐regulates FOXO1 expression levels and thus promotes FOXO1‐mediated STEAP4 transcription, up‐regulating STEAP4 levels. Subsequently, STEAP4 up‐regulates intracellular Cu+ ion levels and causes cuproptosis, which further induces miscarriage.
Shuaishuai Xing, Yanbing Lin, Yi Sun, Xiaoping Yue, Qigang Fan, Jisheng Nie, Zhihong Zhang, Yajing Liu, Juntang Yang, Qingzheng Kang, Yanxin Wang, Haijun Yan, Chan Tian, Ying Chang, Huidong Zhang   +14 more
wiley   +1 more source

Autoimmune central diabetes insipidus in a patient with ureaplasma urealyticum infection and review on new triggers of immune response

Archives of Endocrinology and Metabolism, 2015
Diabetes insipidus is a disease in which large volumes of dilute urine (polyuria) are excreted due to vasopressin (AVP) deficiency [central diabetes insipidus (CDI)] or to AVP resistance (nephrogenic diabetes insipidus).
Giuseppe Murdaca, Rodolfo Russo, Francesca Spanò, Diego Ferone, Manuela Albertelli, Angelo Schenone, Miriam Contatore, Andrea Guastalla, Annamaria De Bellis, Giacomo Garibotto, Francesco Puppo   +10 more
doaj   +1 more source

Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 688-701, October 2025.
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González, Yahira Guzman, Nadia Juliana Proaños, Rosa‐Helena Bustos, María Aconcha, Ivan Guerrero, Laura Alejandra Martinez, Michael Berk, Seetal Dodd   +8 more
wiley   +1 more source

Prevalence, Risk Factors and Complications of Diabetes Insipidus in the Republic of Uzbekistan

Mìžnarodnij Endokrinologìčnij Žurnal, 2013
Despite the fact that diabetes insipidus (DI) is a rare independent disorder, there are many publications on this subject in the contemporary literature. Interest to the problem of DI is due to the fact that the syndrome of diabetes insipidus can be both
Z.Yu. Khalimova, Yu.M. Urmanova, D.A. Aliyeva, M.M. Karimova, Kh.K. Nasyrova, F.S. Khodjayeva, Sh.A. Bobokhodjayeva   +6 more
doaj   +1 more source

Congenital nephrogenic diabetes insipidus accompanied with central nephrogenic diabetes secondary to pituitary surgery -a case report

BMC Endocrine Disorders, 2021
Background Diabetes insipidus (DI) can be a common cause of polydipsia and polyuria. Here, we present a case of congenital nephrogenic diabetes insipidus (CNDI) accompanied with central diabetes insipidus (CDI) secondary to pituitary surgery.
Wei Zhang, Yimin Shen, Yuezhong Ren, Yvbo Xin, Lijun Wang   +4 more
doaj   +1 more source

Mechanisms governing GPCR anterograde transport

FEBS Letters, Volume 599, Issue 17, Page 2420-2438, September 2025.
G protein‐coupled receptors (GPCRs) determine human physiology by transducing ligand binding into intracellular signaling. The transport of nascent GPCRs from the endoplasmic reticulum to the cell surface is critical for cellular responsiveness. We discuss mechanisms regulating GPCR trafficking through secretory organelles, retention of disease‐related
Kevin Assoumou, Sofia Papadogkonaki, Itziar Muneta‐Arrate, Miriam Stoeber   +3 more
wiley   +1 more source

Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus

Nature Communications, 2017
Nrf2 regulates oxidative and electrophilic stress responses by modulating the expression of enzymes involved in detoxification pathways. Here Suzukiet al.
Takafumi Suzuki, Shiori Seki, Keiichiro Hiramoto, Eriko Naganuma, Eri H. Kobayashi, Ayaka Yamaoka, Liam Baird, Nobuyuki Takahashi, Hiroshi Sato, Masayuki Yamamoto   +9 more
doaj   +1 more source

V2 vasopressin receptor mutations: future personalized therapy based on individual molecular biology

Frontiers in Endocrinology, 2023
The diluting and concentrating function of the kidney plays a crucial role in regulating the water homeostasis of the body. This function is regulated by the antidiuretic hormone, arginine vasopressin through the type 2 vasopressin receptor (V2R ...
László Sándor Erdélyi, László Hunyady, László Hunyady, András Balla, András Balla   +4 more
doaj   +1 more source

Hyperkalaemia secondary to suspected transient hyporeninaemic hypoaldosteronism in a dog (in a dog)

Veterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract A 12‐year‐7‐month‐old, female, entire beagle dog was presented to a referral hospital in England for a 10‐day history of tachypnoea and lethargy. Angiostrongylus vasorum ELISA test was positive, and the patient was started on fenbendazole. One week later, it became lethargic, anorexic, polyuric and polydipsic, and it was diagnosed with an open
Maria Jose Marin Lucas, Francesca Venier
wiley   +1 more source

Physiological basis of arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP-resistance (AVP-R, formerly nephrogenic diabetes insipidus) [PDF]

Exploration of Medicine
This review explored the physiological mechanisms underlying arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP resistance (AVP-R, formerly nephrogenic diabetes insipidus), with a focus on water balance regulation. Vital
Osah Martins Onwuka
doaj   +1 more source