Persistent Nephrogenic Diabetes Insipidus After Discontinuation of Lithium: A Case Report [PDF]
In this article, a case with diabetes insipidus starting with lithium tratment and persisting after discontinuation is presented. The patient complained about being thirsty, polydipsia, and polyuria for 5 months.
Aysun Kalenderoğlu +4 more
doaj
Systemic lupus erythematosus (SLE) presenting as diabetes insipidus (DI) is a rare association; there is a case report of neurogenic DI in patients of SLE; however, SLE and nephrogenic DI has not been reported in literature.
Ashaq Hussain Parrey +3 more
doaj +1 more source
Aquaporins: important but elusive drug targets. [PDF]
The aquaporins (AQPs) are a family of small, integral membrane proteins that facilitate water transport across the plasma membranes of cells in response to osmotic gradients.
A Bergamo +194 more
core +1 more source
Physiopathological Implications of 7TM Receptors [PDF]
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core +1 more source
Canalopatias em endocrinologia: achados genéticos recentes e fisiopatologia [PDF]
Ion channels serve diverse cellular functions, mainly in cell signal transduction. In endocrine cells, these channels play a major role in hormonal secretion, Ca2+-mediated cell signaling, transepithelial transport, cell motility and growth, volume ...
Chiamolera, Maria Izabel +7 more
core +2 more sources
Nrf2 activation protects against lithium-induced nephrogenic diabetes insipidus.
Lithium (Li) is the mainstay pharmacotherapeutic mood stabilizer in bipolar disorder. Its efficacious use is complicated by acute and chronic renal side effects, including nephrogenic diabetes insipidus (NDI) and progression to chronic kidney disease ...
Soma Jobbagy +13 more
semanticscholar +1 more source
Persistent lithium-induced neurotoxicity: direct effect of lithium and/or hypernatremia? [PDF]
Lithium has been used in the treatment of bipolar affective disorder (BAD) for more than 50 years. Features of lithium toxicity include drowsiness, slurred speech, ataxia, psychomotor slowing, polyneuropathy, impaired memory, seizures, coma and death ...
Bourgeois, James A. +1 more
core +2 more sources
Acquired Bartter Syndrome in Primary Sjögren Syndrome
Renal tubular involvement in Sjögren's syndrome (SS) often described with renal tubular acidosis, nephrogenic diabetes insipidus, or rarely with Fanconi syndrome.
Aya Fraj +6 more
doaj +1 more source
Congestive heart failure in rats is associated with increased expression and targeting of aquaporin-2 water channel in collecting duct [PDF]
We tested whether severe congestive heart failure (CHF), a condition associated with excess free-water retention, is accompanied by altered regulation of the vasopressin-regulated water channel, aquaporin-2 (AQP2), in the renal collecting duct.
Andersen, D. +8 more
core +2 more sources
Tissue injury after lithium treatment in human and rat postnatal kidney involves glycogen synthase kinase 3β-positive epithelium [PDF]
It was hypothesized that lithium causes accelerated and permanent injury to the postnatally developing kidney through entry into epithelial cells of the distal nephron and inhibition of glycogen synthase kinase-3β (GSK-3β).
Christensen, Sten +5 more
core +1 more source

