Results 81 to 90 of about 23,590 (248)

Acquired central diabetes insipidus secondary to severe, chronic otitis media and interna in an 8‐year‐old Spanish Mastiff dog (canine)

open access: yesVeterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract An 8‐year‐old spayed female Spanish Mastiff dog presented with a five‐month history of polyuria, polydipsia, persistent isosthenuria to hyposthenuria, urinary incontinence, and bilateral otitis externa, progressing to acute vestibular dysfunction.
Kevin Gooch   +6 more
wiley   +1 more source

Physiological basis of arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP-resistance (AVP-R, formerly nephrogenic diabetes insipidus) [PDF]

open access: yesExploration of Medicine
This review explored the physiological mechanisms underlying arginine vasopressin deficiency (AVP-D, formerly central diabetes insipidus) and AVP resistance (AVP-R, formerly nephrogenic diabetes insipidus), with a focus on water balance regulation. Vital
Osah Martins Onwuka
doaj   +1 more source

Plasma Arginine Vasopressin and Serum Copeptin Concentrations at Rest and After Osmotic‐ and Non‐Osmotic‐Based Stimulation Tests in Dogs

open access: yesJournal of Veterinary Internal Medicine, Volume 39, Issue 5, September/October 2025.
ABSTRACT Background Serum copeptin (sCoP) is used as a surrogate for plasma arginine vasopressin (pAVP) measurement in humans. Objective To measure pAVP and sCoP at rest and after osmotic‐ and non‐osmotic stimulation testing in dogs. Animals Eight young castrated/spayed healthy research Beagles, eight young intact dogs, and eight old neutered healthy ...
Mathieu Victor Paulin   +4 more
wiley   +1 more source

Nephrogenic diabetes insipidus associated with tenofovir administration: report of a paediatric case [PDF]

open access: yes, 2012
Tenofovirrenal toxicity, particularly when associated with other antiretrovirals, has been reported in the adult HIV-positive population. Reports in HIVpositive children are very rare.
Costa, A.   +5 more
core  

A novel mutation affecting the arginine-137 residue of AVPR2 in dizygous twins leads to nephrogenic diabetes insipidus and attenuated urine exosome aquaporin-2 [PDF]

open access: yes, 2016
Mutations in the vasopressin V2 receptor gene AVPR2 may cause X-linked nephrogenic diabetes insipidus by defective apical insertion of aquaporin-2 in the renal collecting duct principal cell.
Dieperink, Hans   +6 more
core   +1 more source

Perioperative Management of Lithium Therapy: Considerations and Recommendations

open access: yes
Bipolar Disorders, Volume 28, Issue 1, February 2026.
L. S. Dominicus   +5 more
wiley   +1 more source

Lithium‐induced kidney injury and fibrosis: A versatile model to explore cellular pathways of injury and repair

open access: yesPhysiological Reports, Volume 13, Issue 17, September 2025.
Abstract Lithium‐induced kidney injury is commonly associated with the development of nephrogenic diabetes insipidus. Longer term lithium exposure is associated with the development of chronic interstitial fibrosis. The mechanisms of lithium‐induced kidney injury are multifaceted, affecting many intracellular cell signaling pathways associated with ...
Paulomi Mehta   +2 more
wiley   +1 more source

Use of copeptin in interpretation of the water deprivation test

open access: yesEndocrinology, Diabetes & Metabolism, 2023
Introduction Currently, the water deprivation test remains the standard method for distinguishing primary polydipsia (PP) from cranial diabetes insipidus (cDI) and nephrogenic diabetes insipidus (nDI). There is increasing interest in a direct estimate of
Matthew Rowe   +3 more
doaj   +1 more source

Pleiotropic Effects of the NSAID Fenamates on Chloride Channels: Opportunity for Ion Channelopathies?

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Chloride channels are involved in many cellular processes, including cell volume regulation, modulation of cell excitability, and electrolyte and water secretion. Mutations of these proteins are associated with heterogeneous diseases such as myotonia, cystic fibrosis, epilepsy, deafness, lysosomal storage disease, and various kinds of renal ...
Paola Laghetti   +4 more
wiley   +1 more source

Nephrotoxicity and Modern Volatile Anesthetics: A Narrative Review

open access: yesToxics
Volatile anesthetics, while increasingly utilized in intensive care medicine, are associated with significant renal adverse effects. A critical safety concern—particularly with sevoflurane—involves its potential impact on renal function ...
Benedicte Hauquiert   +15 more
doaj   +1 more source

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