Results 51 to 60 of about 230,179 (219)

PLA2R1 Overexpression Causes Podocyte Injury by Inhibiting the Cell Cycle: A Clinical Cross-Sectional Investigation and Cellular Study

open access: yesInternational Journal of Nephrology and Renovascular Disease
Wei Liang,1,2 Hua Zhang,2 Yi Wu,3 Zhiwei Lai,2 Weiqiang Zhang,3 Yuhao Cao,4 Lishan Tan,2 Zibo Xiong,2 Guang Yang,2 Zuying Xiong1,2 1Department of Nephrology, School of Clinical Medicine, Peking University Shenzhen Hospital, Anhui Medical University ...
Liang W   +9 more
doaj  

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić   +4 more
wiley   +1 more source

Improvement in Unhealthy Behaviors Among Patients with Chronic Kidney Disease Receiving Integrated Care at Community Hospitals in Thailand

open access: yesInternational Journal of Nephrology and Renovascular Disease
Teerawat Thanachayanont,1 Methee Chanpitakkul,1 Salyaveth Lekagul,1 Kriang Tungsanga1,2 1Department of Nephrology, Bhumirajanagarindra Kidney Institute, Bangkok, Thailand; 2Department of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn ...
Thanachayanont T   +3 more
doaj  

Nursing Diagnoses and Interventions in the Field of Action for Patients Undergoing Renal Replacement Therapy: A Scoping Review

open access: yesNursing Open
Aim To identify the primary nursing diagnoses and interventions related to patients with chronic kidney disease undergoing renal replacement therapy, organised according to Marjory Gordon's functional health patterns through a scoping review.
Miguel Angel Cuevas‐Budhart   +8 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

TIMP4 as a Potential Complementary Biomarker and Therapeutic Target in Membranous Nephropathy: A Multi-Omics Investigation with Clinical Validation

open access: yesJournal of Inflammation Research
Qingsong Chen, Gang Wang, Ruo Zhao, Qiyuan Hu, Jiayun Li, Yuting Wang, Jingyang Ran, Qi Huang, Guiquan Yu, Yanjia Luo, Xiaohui Liao Department of Nephrology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of ...
Chen Q   +10 more
doaj  

Low‐intervention clinical trials in Spain: Do they progress?

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Low‐Intervention Clinical Trials (LICTs) are generally pragmatic trials that investigate medicinal products already authorized for use. In 2014, simplified regulatory frameworks were introduced for LICTs with the aim of reducing regulatory burden and operational complexity, to foster non‐commercial clinical trials (NCCTs); the mandatory ...
Claudia Erika Delgado‐Espinoza   +4 more
wiley   +1 more source

Network Pharmacology Analysis and Machine-Learning Models Confirmed the Ability of YiShen HuoXue Decoction to Alleviate Renal Fibrosis by Inhibiting Pyroptosis [Retraction]

open access: yesDrug Design, Development and Therapy
Feng M, Luo F, Wu H, et al. Drug Des Devel Ther. 2023;17:3169—3192. https://doi.org/10.2147/DDDT.S420135 We, the Editor and Publisher of Drug Design, Development and Therapy, have retracted the published article.
Feng M   +7 more
doaj  

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts   +7 more
wiley   +1 more source

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