Results 71 to 80 of about 357,788 (307)

Do acute elevations of serum creatinine in primary care engender an increased mortality risk? [PDF]

, 2014
Background: The significant impact Acute Kidney Injury (AKI) has on patient morbidity and mortality emphasizes the need for early recognition and effective treatment.
A Bottle, A Lassnigg, A Wonnacott, AS Levey, B Talabani, Christopher KT Farmer, CY Hsu, Department of Health, EA Hoste, EM Burns, GM Chertow, Helen Hobbs, J Stewart, Jean Irving, JP Lafrance, L Gruberg, M Bedford, M Bedford, Michael Bedford, ML Praught, MM Levy, MM Schissler, Office of National Statistics, PA McCullough, Paul Bassett, Paul E Stevens, PG Metnitz, PK Li, R Bellomo, R Mehta, RL Mehta, RL Mehta, RW Schrier, S Uchino, SS Waikar, Toby Wheeler   +35 more
core   +1 more source

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source

The Impact of Needle-Directed Thrombolysis in Thrombosed Arteriovenous Fistulas on Angioplasty Efficacy and the Prognostic Factors Associated with Success

International Journal of Nephrology and Renovascular Disease
Yu Zhou,1,* Qiong Lyu,2,* Qiquan Lai,1 Xuejing Gao,1 Ling Chen,1 Xi Zhang,1 Ziming Wan1 1Department of Nephrology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of ...
Zhou Y, Lyu Q, Lai Q, Gao X, Chen L, Zhang X, Wan Z   +6 more
doaj  

Next Generation Sequencing: A Tool for This Generation of Nephrologists [PDF]

European Medical Journal, 2016
The emergence of next generation sequencing (NGS) techniques has made the sequencing of whole genomes, transcriptomes, and epigenomes faster and more readily available than previous methods such as Sanger sequencing, which was developed in the 1970s.
Lea Landolt, Philipp Strauss, Hans-Peter Marti, Øystein Eikrem   +3 more
doaj  

СТРАНИЦЫ ИСТОРИИ НЕФРОЛОГИИ ДОНА ПЕРВОЙ ПОЛОВИНЫ XX ВЕКА

Архивъ внутренней медицины, 2013
In this article you can find main stages of development of nephrology in first half of XX century in Rostov aria. Information about professors, which work was concentrated on nephrology pathology provided in article. Among them: Z.V.
М. М. Батюшин, В. П. Терентьев   +1 more
doaj   +1 more source

What is the real impact of acute kidney injury? [PDF]

, 2014
Background: Acute kidney injury (AKI) is a common clinical problem. Studies have documented the incidence of AKI in a variety of populations but to date we do not believe the real incidence of AKI has been accurately documented in a district general ...
A Arije, A Lewington, Census population, Christopher KT Farmer, DJ Askenazi, EA Hoste, ED Siew, ED Siew, ED Siew, GM Chertow, H Quan, Health and Social Care Information Centre, HS Kohli, J Hegarty, J Stewart, JE Hux, JL Xue, JP Lafrance, KS Chugh, Michael Bedford, MM Levy, NV Kolhe, O Liangos, P Vachvanichsanong, Paul E Stevens, PE Stevens, PG Metnitz, R Bellomo, RL Mehta, RL Mehta, S Uchino, SS Waikar, T Ali, Toby WK Wheeler, W Metcalfe   +34 more
core   +2 more sources

Establishment of a mouse model of propylthiouracil‐induced antineutrophil cytoplasmic antibody‐associated vasculitis

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract summarizes our study in which we established a novel murine model of antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis. Neutrophil recruitment was induced using thioglycolate, followed by timed administration of propylthiouracil and phorbol 12‐myristate 13‐acetate to generate DNase I‐resistant neutrophil ...
Sakiko Masuda, Momo Uchizawa, Chihiro Terasaka, Takumi Abe, Tetsuro Nakamura, Yuka Nishibata, Yusho Ueda, Daigo Nakazawa, Utano Tomaru, Akihiro Ishizu   +9 more
wiley   +1 more source

Malnutrition and Muscle Loss Mediate the Association Between NT-proBNP and Mortality in Hospitalized Older Adults

Clinical Interventions in Aging
Jun Tao,1,2 Xiaoyan Zhang,2 Niansong Wang,1 Dongsheng Cheng1 1Department of Nephrology, Shanghai Sixth People’s Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Geriatrics ...
Tao J, Zhang X, Wang N, Cheng D
doaj  

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Comparative Efficacy and Safety of Drug-Coated Balloon Angioplasty versus Conventional Balloon Angioplasty for Arteriovenous Access Stenosis in Hemodialysis Patients

International Journal of General Medicine
Ce Zhang,1 Jingyu Cai,1 Qiuxiang Chen,1 Xia Mi,1 Ye Li2 1Department of Nephrology, Nanjing Drum Tower Hospital Group Suqian Hospital (The Affiliated Suqian Hospital of Xuzhou Medical University), Suqian, Jiangsu, 223800, People’s Republic of China ...
Zhang C, Cai J, Chen Q, Mi X, Li Y
doaj