Results 81 to 90 of about 323,772 (303)

Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification

open access: yesAngewandte Chemie, EarlyView.
Bioactive superstructures are assembled via metal–phenolic‐mediated assembly on agarose templates, followed by modification with human serum albumin. These superstructures demonstrate high bilirubin adsorption efficiency, strong antibacterial activity, and anticoagulant activity, providing a strategy for the rational design of multifunctional blood ...
Po Wang   +12 more
wiley   +2 more sources

Early nephrology consultation can have an impact on outcome of acute kidney injury patients

open access: yes, 2011
Background. Patients who develop acute kidney injury (AKI) in the intensive care unit (ICU) have extremely high rates of mortality and morbidity. The objectives of this study were to compare clinical and laboratory characteristics of AKI patients ...
Balbi, André Luis [UNESP]   +11 more
core   +1 more source

Comparative Efficacy and Safety of Drug-Coated Balloon Angioplasty versus Conventional Balloon Angioplasty for Arteriovenous Access Stenosis in Hemodialysis Patients

open access: yesInternational Journal of General Medicine
Ce Zhang,1 Jingyu Cai,1 Qiuxiang Chen,1 Xia Mi,1 Ye Li2 1Department of Nephrology, Nanjing Drum Tower Hospital Group Suqian Hospital (The Affiliated Suqian Hospital of Xuzhou Medical University), Suqian, Jiangsu, 223800, People’s Republic of China ...
Zhang C, Cai J, Chen Q, Mi X, Li Y
doaj  

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

open access: yesAdvanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li   +10 more
wiley   +1 more source

Organizational Climate, Evidence-Based Nursing Competence, and Professional Identity Among Clinical Nurses: A Multicenter Cross-Sectional Study Using Mediation and Latent Profile Analyses

open access: yesJournal of Multidisciplinary Healthcare
Chang Guo,1,* SiYuan Zhao,2,* BeiTao Gong,3 CaiXia Li,4 ShaoMin Huang,1 Lian Lin,1 ShouZhen Cheng,5 XiaoFei Tian11Department of Nursing, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, 518107, People’s Republic of ...
Guo C   +7 more
doaj  

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

open access: yesAdvanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi   +11 more
wiley   +1 more source

Exploring the Underlying Mechanism of Shenyankangfu Tablet in the Treatment of Glomerulonephritis Through Network Pharmacology, Machine Learning, Molecular Docking, and Experimental Validation [Retraction]

open access: yesDrug Design, Development and Therapy
Jin M, Ren W, Zhang W, Liu L, Yin Z, Li D. Drug Des Devel Ther. 2021;15:4585-4601. We, the Editors and Publisher of the journal, Drug Design, Development and Therapy have retracted the published article.
Jin M   +5 more
doaj  

Quantifying “Medical Renal Disease”: A Pediatric Pilot Study Using Ultrasound Radiomics for Differentiating Acute Kidney Injury and Chronic Kidney Disease

open access: yesDiagnostics
Background: Differentiating acute kidney injury (AKI) from chronic kidney disease (CKD) in children remains a critical unmet need due to the limitations of current clinical and biochemical markers. Conventional ultrasound lacks the sensitivity to discern
Laura De Leon-Benedetti   +9 more
doaj   +1 more source

Tumor Necrosis Factor-α Gene Polymorphism is Associated with Short- and Long-Term Kidney Allograft Outcomes

open access: yesJournal of Inflammation Research, 2022
Felix Poppelaars,1 Mariana Gaya da Costa,1,2 Bernardo Faria,1,3 Siawosh K Eskandari,1 Marc A Seelen,1 Jeffrey Damman4 1Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The ...
Poppelaars F   +5 more
doaj  

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

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