Clinical and Developmental Immunology, 2013 Nephropathia epidemica (NE) caused by Puumala hantavirus (PUUV) is the most common hemorrhagic fever with renal syndrome (HFRS) in Europe. The infection activates immunological mechanisms that contribute to the pathogenesis and characteristics of the ...
Timo Hautala +8 more
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The severity of Puumala hantavirus induced nephropathia epidemica can be better evaluated using plasma interleukin-6 than C-reactive protein determinations [PDF]
BMC Infectious Diseases, 2010 Background Nephropathia epidemica (NE) is a Scandinavian type of hemorrhagic fever with renal syndrome caused by Puumala hantavirus. The clinical course of the disease varies greatly in severity.
Pörsti Ilkka H +8 more
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Human Hantavirus Infections in Hungary (2018–2025): Epidemiology, Molecular Detection Across Clinical Sample Types, and Phylogenetic Analysis [PDF]
VirusesHantaviruses are globally distributed, rodent-borne zoonotic pathogens. In Hungary, Dobrava-Belgrade virus (DOBV) and Puumala virus (PUUV) are circulating, causing hemorrhagic fever with renal syndrome and nephropathia epidemica, respectively. Due to the
Anita Koroknai +6 more
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Puumala orthohantavirus: prevalence, biology, disease, animal models and recent advances in therapeutics development and structural biology [PDF]
Frontiers in ImmunologyPuumala orthohantavirus (PUUV) is an emerging zoonotic virus that was first discovered in the Puumala region of Finland in the early 1980s and is the primary etiological agent of nephropathia epidemica (NE), a milder form of a life-threatening disease ...
Alina Tscherne +8 more
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Impact of Environmental Factors on the Distribution Patterns of Nephropathia Epidemica Cases in Western Europe. [PDF]
Environ Health Perspectpeer reviewedEnvironmental factors, such as fluctuations of climatic conditions and land cover, play a pivotal role in driving infectious disease epidemics, particularly those originating from wildlife reservoirs.
Erazo D +9 more
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Differential Cytokine Responses and the Clinical Severity of Adult and Pediatric Nephropathia Epidemica. [PDF]
Int J Mol Sci, 2023 Nephropathia epidemica (NE), caused by the hantavirus infection, is endemic in Tatarstan Russia. The majority of patients are adults, with infection rarely diagnosed in children.
Martynova E +10 more
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Zoonoses and Public Health, Volume 69, Issue 5, Page 579-586, August 2022., 2022 Abstract Puumala orthohantavirus (PUUV) is the most important hantavirus species in Europe, causing the majority of human hantavirus disease cases. In central and western Europe, the occurrence of human infections is mainly driven by bank vole population dynamics influenced by beech mast.
Christina Princk +13 more
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Long-Term Consequences of Puumala Hantavirus Infection
Viruses, 2022 Several viral infections are associated with acute and long-term complications. During the past two years, there have been many reports on post-infectious symptoms of the patients suffering from COVID-19 disease.
Jukka Mustonen +3 more
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Central Nervous System and Ocular Manifestations in Puumala Hantavirus Infection
Viruses, 2021 Puumala hantavirus (PUUV), carried and spread by the bank vole (Myodes glareolus), causes a mild form of hemorrhagic fever with renal syndrome (HFRS) called nephropathia epidemica (NE).
Nina Hautala +4 more
doaj +1 more source
Clinical &Translational Immunology, Volume 10, Issue 8, 2021., 2021 In this review, we summarise the current human evidence of the use of cerebrospinal fluid metabolomics to detect neuroinflammation in acute and chronic neurological and psychiatric diseases. The review highlights the potential utility of metabolites involved in the tryptophan–kynurenine and nitric oxide pathway and neopterin as biomarkers for ...
Jingya Yan +4 more
wiley +1 more source