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Pharmacological correction of intrarenal hemodynamic disorders in acute kidney injury (part 2) [PDF]

Research Results in Pharmacology, 2018
Introduction: Treatment of acute kidney injury (AKI) is a complex current problem. Mortality in this pathology is over 50%. One of the areas of correction therapy in AKI patients is the improvement of diagnostics and the earliest identification of the ...
Katherine K. Shramenko, Georgiy A. Gorodnik, Valentina P. Shano, Irina V. Kuznetsova, Aleksandr P. Grigorenko, Vladimir V. Potapov   +5 more
doaj   +7 more sources

Phytotherapeutic drugs with nephroprotective activity (review). [PDF]

Medičnì Perspektivi, 2017
The article analyzes characteristics of chemical composition and pharmacodynamics of phytotherapeutic agents (monopreparations and complexes), used in the treatment of kidney and urinary tract diseases.
E. A. Podpletnyaia, N. V. Khomiak, E. V. Sokolova, S. P. Kaydash, E. V. Khomiak   +4 more
doaj   +5 more sources

Cost-effectiveness analysis of nephroprotection programs for patients with type 2 diabetes mellitus in insurers in Colombia [PDF]

Cost Effectiveness and Resource Allocation
Background This research aimed to determine the cost-effectiveness of nephroprotection programs compared to no intervention in adults with type 2 diabetes mellitus (T2DM) in the Colombian national health system.
Cristian Alejandro González-Rojas, Sergio Augusto Cáceres-Maldonado, Luis Alberto Soler-Vanoy, Lizbeth Alexandra Acuña-Merchán   +3 more
doaj   +2 more sources

Cordycepin nephroprotection: From STZ mouse to human T2D. [PDF]

J Diabetes Investig
Journal of Diabetes Investigation, Volume 16, Issue 12, Page 2250-2250, December 2025.
Yang J.
europepmc   +2 more sources

Regression Modeling of the Antioxidant-to-Nephroprotective Relation Shows the Pivotal Role of Oxidative Stress in Cisplatin Nephrotoxicity

Antioxidants, 2021
The clinical utility of the chemotherapeutic drug cisplatin is significantly limited by its nephrotoxicity, which is characterized by electrolytic disorders, glomerular filtration rate decline, and azotemia.
Alfredo G. Casanova, Mykola Harvat, Laura Vicente-Vicente, Óscar J. Pellicer-Valero, Ana I. Morales, Francisco J. López-Hernández, José D. Martín-Guerrero   +6 more
doaj   +1 more source

Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease

Frontiers in Pharmacology, 2021
Diabetic kidney disease (DKD) is the leading cause of end-stage renal failure, but therapeutic options for nephroprotection are limited. Oxidative stress plays a key role in the pathogenesis of DKD.
Mei Jing, Mei Jing, Yun Cen, Fangfang Gao, Ting Wang, Jinxin Jiang, Qianqian Jian, Liangmiao Wu, Liangmiao Wu, Baojian Guo, Fangcheng Luo, Fangcheng Luo, Gaoxiao Zhang, Ying Wang, Lipeng Xu, Zaijun Zhang, Yewei Sun, Yuqiang Wang   +17 more
doaj   +1 more source

Nephroprotective Properties of Antidiabetic Drugs

Journal of Clinical Medicine, 2023
Chronic kidney disease (CKD) is associated with increased morbidity and mortality, especially from cardiovascular (CV) causes, and especially in people with diabetes mellitus (DM). Already the presence of DM increases CV risk and potentiates the risk of CKD.
Christian Gerdes, Nicolle Müller, Gunter Wolf, Martin Busch   +3 more
openaire   +2 more sources

Pioglitazone - the forgotten drug with multidirectional action

Journal of Education, Health and Sport, 2023
Introduction: Pioglitazone (PG) which belongs to thiazolidinedione class is a drug used in the treatment of type 2 diabetes. PG increases the insulin sensitivity of peripheral tissues.
Arkadiusz Aab, Julia Zarańska
doaj   +1 more source

Renal mitochondrial restoration by gymnemic acid in gentamicin-mediated experimental nephrotoxicity: evidence from serum, kidney and histopathological alterations

Frontiers in Pharmacology, 2023
Background: Nephrotoxicity refers to the toxigenic impact of compounds and medications on kidney function. There are a variety of drug formulations, and some medicines that may affect renal function in multiple ways via nephrotoxins production ...
Shubhangi Gumbar, Sudeep Bhardwaj, Sidharth Mehan, Zuber Khan, Acharan S. Narula, Reni Kalfin, Reni Kalfin, Shams Tabrez, Shams Tabrez, Torki A. Zughaibi, Torki A. Zughaibi, Samina Wasi   +11 more
doaj   +1 more source

Pharmacological Nephroprotection in Chronic Kidney Disease Patients with Type 2 Diabetes Mellitus-Clinical Practice Position Statement of the Polish Society of Nephrology. [PDF]

Int J Mol Sci
Adamczak M, Kurnatowska I, Naumnik B, Stompór T, Tylicki L, Krajewska M.   +5 more
europepmc   +2 more sources