Results 21 to 30 of about 1,321 (178)
Alcohol, Clinical and Experimental Research, Volume 49, Issue 5, Page 1097-1105, May 2025.Alcohol consumption showed a U‐shaped relationship with all‐cause mortality, while adiponectin levels were dose‐dependently linked to mortality. Furthermore, an interaction between alcohol intake and adiponectin levels was noted, regardless of conventional cardiovascular risk factors. For a deeper understanding of the mechanisms driving this connection
Ryuichi Kawamoto +4 more
wiley +1 more source
Spatiotemporal landscape of kidney in a mouse model of hyperuricemia at single‐cell level
The FASEB Journal, Volume 39, Issue 2, 31 January 2025.We utilized crispr‐cas9 to create Uox‐KO mice, which could be an ideal mouse model for hyperuricemia. Then, we figured the spatiotemporal atlas of hyperuricemic nephropathy by applying single‐cell RNA sequencing, spatial transcriptomics, spatial proteomics, and spatial metabolomics in the Uox‐KO mouse model.
Haining Chang +4 more
wiley +1 more source
Targeting Fibrosis: From Molecular Mechanisms to Advanced Therapies
Advanced Science, Volume 12, Issue 3, January 20, 2025.This review comprehensively summarizes the advances in research for fibrosis. It emphasizes organ‐specific profibrotic cell types and molecular mechanisms of fibrosis, especially in the kidney, liver, lung, and heart. The authors highlight the advanced antifibrotic small molecule drugs and cellular therapies for fibrosis.
Xingpeng Di +4 more
wiley +1 more source
Veterinary Clinical Pathology, Volume 53, Issue 2, Page 168-178, June 2024.Abstract Background Lipofuscin‐like cytoplasmic inclusions have been reported in human blood neutrophils and monocytes but have not been described in dogs. In people, these “green granules of death” have been associated with moderate to severe hepatocellular injury and high mortality.
Kimberley N. Sebastian +2 more
wiley +1 more source
BioMed Research International, Volume 2024, Issue 1, 2024.Background: 18KHT01 is a novel synergistic composition of Quercus acutissima, Camellia sinensis, Geranium thunbergii, and a small portion of Citrus limon. Our previous report demonstrated that the 18KHT01 exhibits potent antiobesity effects, with synergistic antioxidant, antiadipogenic, and antiobesity activities in diet‐induced obese mice.
Prakash Raj Pandeya +5 more
wiley +1 more source
, 1957 As seen, is under review the concept of nephrosis lipoid as primary renal tubular disease and exclusive; Today it is considered that the renal tubules to undergo aggression it will share in the glomerulus; would thus missing the concept of lipoic ...
Zegarra Puppi, José
core +1 more source
, 1900 Lipoid nephrosis: The medullary portions are congested; otherwise, no changes ...
MUSC Department of Pathology and Laboratory Medicine
core
The treatment of IgA nephropathy
, 2015 Background: IgA nephropathy (IgAN) is a very common glomerulonephritis worldwide. Nevertheless, treatment options for primary IgAN are still largely based on opinion or weak evidence.
Lai, KN, Leung, JCK, Tang, SCW
core +1 more source
A rapid ultrastructural embedding procedure for renal biopsy tissue
, 1982 The increasing reliance of pathologists on ultrastructural morphology for the diagnosis of human biopsy material has created a need for rapid ultrastructural embedding procedures (RUEP) to accelerate the preparation of material.
Ainsworth, Sterling K. +2 more
core +1 more source