Systemic inflammation accelerates the development of focal segmental glomerulosclerosis in a mouse model of adriamycin induced nephrosis [PDF]
Research indicates that minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) may reflect varying severities of the same underlying condition, with inflammation potentially facilitating the progression from MCD to FSGS.
Lian Liu, Qiu Li, Gaofu Zhang
doaj +2 more sources
Dysregulation of Podocyte BK Channels and Nephrosis: Effects of Circulating Factors and Auxiliary β4 Subunits [PDF]
Podocytes express large-conductance Ca2+-activated K+ channels (BK channels) and at least two different pore-forming KCa1.1 subunit C-terminal splice variants, known as VEDEC and EMVYR, along with auxiliary β and γ subunits.
Eun Young Kim +2 more
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Serological responses to immunization during nephrosis in infants with congenital nephrotic syndrome of the Finnish type [PDF]
BackgroundPretransplant vaccination is generally recommended to solid organ transplant recipients. In infants with congenital nephrotic syndrome (CNS), the immune response is hypothetically inferior to other patients due to young age and urinary loss of ...
Okko Savonius +6 more
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Role of the Ste20‐like kinase SLK in podocyte adhesion [PDF]
SLK controls the cytoskeleton, cell adhesion, and migration. Podocyte‐specific deletion of SLK in mice leads to podocyte injury as mice age and exacerbates injury in experimental focal segment glomerulosclerosis (FSGS; adriamycin nephrosis).
Andrey V. Cybulsky +4 more
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Oxidative stress markers in initial therapy and remission of nephrotic syndrome and serum malondialdehyde level predictor from routine laboratory test [PDF]
Aim To compare oxidative stress state of children with nephrotic syndrome at the first week of treatment and in remission, and to predict malondialdehyde (MDA) level from routine laboratory tests.
Riska Habriel Ruslie +3 more
doaj +1 more source
Proteinase 3 (PR3)-Antineutrophil Cytoplasmic Antibody in a Patient with Minimal Change Disease: An Unusual Finding [PDF]
Antineutrophil cytoplasmic antibodies (ANCA) are useful as markers for systemic vasculitis. PR3-ANCA antibodies have been also identified in association with chronic inflammatory and infectious conditions, other autoimmune diseases, malignancy, and ...
Joana Freitas +6 more
doaj +1 more source
Multiple Spontaneous Remitting and Relapsing Nephrotic Syndrome in a Cirrhotic Patient
Reports of spontaneous remissions in minimal change disease are rare and often associated with secondary causes. We report the case of a 47-year-old male patient with HIV-HBV/HDV co-infection and cirrhosis, admitted in the emergency department with ...
Eunice Cacheira, Ivo Laranjinha
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Atypical chronic copper poisoning in a sheep secondary to copper wire ingestion - case report
A 14-month-old female Texel sheep that came from a herd made up of 19 animals showed haemoglobinuria, apathy, and anorexia, and died two days after the start of the clinical signals. The sheep remained in a natural grassland, where trailers were repaired,
L.S. Quevedo +7 more
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A Patient with Henoch-Schönlein Purpura with Intussusception and intractable Nephritis [PDF]
Henoch-Schönlein purpura (HSP) is the most common vasculitis in children, mainly affecting the small vessels of the skin, joints, gastrointestinal tract, and kidneys.
Min Kyoung Seo +3 more
doaj +1 more source
Spontaneous and experimental poisoning by nitroxinil at 34% in goats
: This study describes the epidemiological, clinical, and pathological aspects of spontaneous and experimental poisoning by nitroxinil at 34% concentration in goats. The outbreak occurred on a farm in the municipality of Prata, Paraíba state.
João Ricardo C. Brito Junior +7 more
doaj +1 more source

