Results 11 to 20 of about 10,065 (131)

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

open access: yesAdvanced Science
Focal segmental glomerulosclerosis (FSGS) is a common glomerular lesion that manifests as a primary podocyte injury. Multiple genetic risk factors have been reported to be associated with the development of FSGS.
Fubin Zhu   +14 more
doaj   +2 more sources

Spontaneous Remission of Late Relapsing Membranous Nephropathy After Previous Immunosuppressant-Induced Remission: Case Report. [PDF]

open access: yesCase Rep Nephrol
This is the first detailed report of spontaneous remission of late relapsing membranous nephropathy (MN) after previous immunosuppressant‐induced remission. In March 2004, a 52‐year‐old Hispanic male presented with severe nephrotic syndrome with proteinuria of 13 g/24 h. The workup for infectious and autoimmune diseases was unrevealing.
Cao Y.
europepmc   +2 more sources

Lupus, a Leading Cause of Years of Potential Life Lost in Young Women: Implications for Public Health Priorities and Research Funding. [PDF]

open access: yesACR Open Rheumatol
Objective Premature mortality burden is an important component of disease burden and can help guide health care and research priorities. However, relying solely on mortality rates may underestimate lupus mortality burden because a substantial proportion of deaths occur at younger ages. Years of potential life lost (YPLL) captures premature mortality by
Yen EY, Park EJ, Singh RR.
europepmc   +2 more sources

Hypertriglyceridemia in nephrotic rats is due to a clearance defect of plasma triglyceride: overproduction of triglyceride-rich lipoprotein is not an obligatory factor

open access: yesJournal of Lipid Research, 1993
This study was conducted to determine whether overproduction of triglyceride-rich lipoprotein is an obligatory factor for experimental hypertriglyceridemia in nephrotic rats.
G Yoshino   +7 more
doaj   +1 more source

Juvenile Dermatomyositis with Generalized Edema

open access: yesPediatric Neurology Briefs, 2001
A 7-year-old girl presenting with an 8-week history of fatigue, myalgia, dyspnea, and generalized, nonpitting edema of the extremities, face, chest, and abdomen, is reported from the Walter Reed Army Medical Center, Washington, DC.
J Gordon Millichap
doaj   +1 more source

One Case about Primary Pulmonary Squamous Cell Carcinoma 
with Retinal Metastasis

open access: yesChinese Journal of Lung Cancer, 2017
Lung cancer is a common malignant tumor in clinic. Morbidity and mortality are the first place in cancer, which seriously threaten the health of human beings.
Jinxia LIU, Xiqian GAO, Mindan SUN
doaj   +1 more source

Histological changes caused by experimental Riedeliella graciliflora (Leg. Papilionoideae) poisoning in cattle and laboratory animals Alterações histológicas na intoxicação experimental por Riedeliella graciliflora (Leg. Papilionoideae) em bovinos e animais de laboratório

open access: yesPesquisa Veterinária Brasileira, 2001
Tissues from cattle, mice, rats and guinea pigs experimentally intoxicated by Riedeliella graciliflora were studied histologically. Cattle lymph nodes, spleen, Peyer patches and peribronchial lymphoid tissues had diffuse necrosis of lymphocytes, mainly ...
Franklin Riet-Correa   +3 more
doaj   +1 more source

Nephron Number and Time to Remission in Steroid-Sensitive Minimal Change DiseasePlain-Language Summary

open access: yesKidney Medicine, 2020
Rationale & Objective: The response to corticosteroid therapy may differ among patients with minimal change disease (MCD). Previous studies have suggested that glomerular hypertrophy or low areal glomerular density in biopsy specimens, which may be ...
Takaya Sasaki   +9 more
doaj   +1 more source

Prenatal diagnostic and management of megacystis microcolon intestinal hypoperistalsis syndrome: A report on a rare case in Cipto Mangunkusumo Hospital, Jakarta, Indonesia

open access: yesMajalah Obstetri dan Ginekologi, 2020
Megacystis Microcolon Intestinal Hypoperistalsis Syndrome (MMIHS) is a rare and the most severe form of functional intestinal obstruction in the newborn. The characteristic features of this congenital and fatal disease are abdominal distension, absent or
Fita Maulina, Yuditiya Purwosunu
doaj   +1 more source

TRPC5 Channel Inhibition Protects Podocytes in Puromycin-Aminonucleoside Induced Nephrosis Models

open access: yesFrontiers in Medicine, 2021
Podocyte injury and the appearance of proteinuria are key features of several progressive kidney diseases. Genetic deletion or selective inhibition of TRPC5 channels with small-molecule inhibitors protects podocytes in rodent models of kidney disease ...
Yiming Zhou   +14 more
doaj   +1 more source

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