Results 41 to 50 of about 10,065 (131)

Human serum albumin homeostasis: a new look at the roles of synthesis, catabolism, renal and gastrointestinal excretion, and the clinical value of serum albumin measurements

open access: yesInternational Journal of General Medicine, 2016
David G Levitt,1,* Michael D Levitt2,* 1Department of Integrative Biology and Physiology, University of Minnesota, 2Research Service, Veterans Affairs Medical Center, Minneapolis, MN, USA *These authors contributed equally to this work Abstract: Serum ...
Levitt DG, Levitt MD
doaj  

Efficacy of AAV9-mediated SGPL1 gene transfer in a mouse model of S1P lyase insufficiency syndrome

open access: yesJCI Insight, 2021
Sphingosine-1-phosphate lyase insufficiency syndrome (SPLIS) is a rare metabolic disorder caused by inactivating mutations in sphingosine-1-phosphate lyase 1 (SGPL1), which is required for the final step of sphingolipid metabolism. SPLIS features include
Piming Zhao   +14 more
doaj   +1 more source

Cancer statistics, 2026

open access: yesCA: A Cancer Journal for Clinicians, Volume 76, Issue 1, January/February 2026.
ABSTRACT Each year, the American Cancer Society estimates the numbers of new cancer cases and deaths in the United States and compiles the most recent data on population‐based cancer occurrence and outcomes using data collected by central cancer registries (incidence, through 2022) and the National Center for Health Statistics (mortality, through 2023).
Rebecca L. Siegel   +4 more
wiley   +1 more source

Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin   +6 more
wiley   +1 more source

Characteristics and prognostic factors of chronic kidney disease patients with Pneumocystis jirovecii pneumonia

open access: yesLinchuang shenzangbing zazhi
ObjectiveTo explore the clinical and prognostic characteristics of chronic kidney disease (CKD) patients with Pneumocystis jirovecii pneumonia (PJP), thus facilitating the diagnosis and treatment of Pneumocystis jirovecii infections.MethodsWe ...
Liu Xiao-hua   +6 more
doaj   +1 more source

Peritoneal Lymphomatosis as Posttransplant Lymphoproliferative Disorder

open access: yes
eJHaem, Volume 7, Issue 2, April 2026.
Shiori Nishitani   +7 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

Harnessing chimeric antigen receptor macrophages against solid tumors

open access: yesCancer Communications, Volume 45, Issue 11, Page 1344-1366, November 2025.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang   +3 more
wiley   +1 more source

Case Report: Spinal muscular atrophy with IgA nephropathy: a coincidence or association?

open access: yesFrontiers in Pediatrics
BackgroundSpinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder caused by biallelic loss-of-function variants of the survival motor neuron 1 (SMN1) gene on chromosome 5q13. It has been reported that SMA may affect the function of
Yuxuan Gu   +12 more
doaj   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

open access: yesDevelopmental Medicine &Child Neurology, Volume 67, Issue 11, Page 1383-1408, November 2025.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16431 Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment.
Ana Alarcón   +33 more
wiley   +1 more source

Home - About - Disclaimer - Privacy