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Nephrotic Syndrome

Primary Care: Clinics in Office Practice, 2020
Nephrotic syndrome is one cause of end-stage kidney disease. Because edema is a common presenting feature and hypertension and dyslipidemia are often present in nephrotic syndrome, it is important for the primary care physician to suspect this entity.
Seth Anthony, Politano, Gates B, Colbert, Nida, Hamiduzzaman   +2 more
semanticscholar   +5 more sources

Whole Exome Sequencing of Patients with Steroid-Resistant Nephrotic Syndrome [PDF]

American Society of Nephrology. Clinical Journal, 2018
BACKGROUND AND OBJECTIVES: Steroid-resistant nephrotic syndrome overwhelmingly progresses to ESRD. More than 30 monogenic genes have been identified to cause steroid-resistant nephrotic syndrome.
Ashraf, S, Bakkaloglu, SA, Baum, M, Benador, N, Bockenhauer, D, Bogdanovic, R, Braun, DA, Buscher, R, Cadnapaphornchai, MA, Chen, J, Chernin, G, Daga, A, Daouk, G, El Desoky, S, Ettenger, R, Fathy, H, Fehrenbach, H, Ferguson, MA, Gee, HY, Hashmi, S, Hermle, T, Hildebrandt, F, Hopcian, J, Ityel, H, Jobst-Schwan, T, Kari, JA, Kemper, M, Kohl, S, Kopp, JB, Lawson, JA, Lifton, RP, Lovric, S, Majmundar, AJ, Mane, S, Mueller, D, Munarriz, RL, Nakayama, M, Noyan, A, Ozaltin, F, Pabst, WL, Podracka, L, Rao, J, Rodig, NM, Sadowski, CE, Schapiro, D, Schmidt, JM, Schneider, R, Serdaroglu, E, Shril, S, Soliman, NA, Somers, MJG, Stajic, N, Stein, DR, Tan, W, Tasic, V, Traum, AZ, van der Ven, AT, Vivante, A, Warejko, JK, Widmeier, E, Zenker, M   +60 more
core   +2 more sources

Safety and Efficacy of Pneumococcal Vaccination in Pediatric Nephrotic Syndrome

Frontiers in Pediatrics, 2019
Nephrotic syndrome affects both children and adults. Idiopathic nephrotic syndrome is reported to be one of the most frequent renal pathologies in childhood.
Shamitha Thishakya Goonewardene, Shamitha Thishakya Goonewardene, Shamitha Thishakya Goonewardene, Calyn Tang, Calyn Tang, Calyn Tang, Loh Teng-Hern Tan, Loh Teng-Hern Tan, Kok-Gan Chan, Kok-Gan Chan, Prithvy Lingham, Learn-Han Lee, Learn-Han Lee, Bey-Hing Goh, Bey-Hing Goh, Priyia Pusparajah, Priyia Pusparajah   +16 more
doaj   +2 more sources

A Case of Refractory Nephrotic Syndrome Complicated With Tuberculous Pleurisy and Literature Review [PDF]

Clinical Case Reports
Nephrotic syndrome(NS) can be classified into steroid‐sensitive nephrotic syndrome (SSNS) and steroid‐resistant nephrotic syndrome (SRNS). Rifampicin is potentially leading to treatment resistance in NS.
Jiang‐min Wan, Qi Luo, Ping Huang, Xun‐shun Jiang, Zheng‐lan Gao, Xiao‐gang Du   +5 more
doaj   +2 more sources

Impact of COVID-19 on the clinical course of nephrotic syndrome in children: a single-center study [PDF]

Childhood Kidney Diseases, 2022
Purpose Children with nephrotic syndrome may experience disease relapse or aggravation triggered by various viral infections. Limited studies on the clinical implications of the coronavirus disease 2019 (COVID-19) pandemic in children with nephrotic ...
Min Ji Park, Jung Kwan Eun, Hee Sun Baek, Min Hyun Cho   +3 more
doaj   +1 more source

IPNA clinical practice recommendations for the diagnosis and management of children with steroid-sensitive nephrotic syndrome

Pediatric nephrology (Berlin, West), 2022
Idiopathic nephrotic syndrome is the most frequent pediatric glomerular disease, affecting from 1.15 to 16.9 per 100,000 children per year globally. It is characterized by massive proteinuria, hypoalbuminemia, and/or concomitant edema.
A. Trautmann, O. Boyer, E. Hodson, A. Bagga, D. Gipson, S. Samuel, J. Wetzels, K. Alhasan, S. Banerjee, R. Bhimma, M. Bonilla-Félix, F. Cano, M. Christian, D. Hahn, H. Kang, Koichi Nakanishi, H. Safouh, H. Trachtman, Hong Xu, Wendy Cook, M. Vivarelli, D. Haffner, Antonia Claire Francesco Markus Rezan Aoife Lutz Alexandra Bouts Dossier Emma Kemper Topaloglu Waters Thorste, A. Bouts, C. Dossier, F. Emma, M. Kemper, R. Topaloğlu, A. Waters, Lutz Thorsten Weber, A. Zurowska, K. Gibson, L. Greenbaum, S. Massengill, D. Selewski, T. Srivastava, Chia-shi Wang, Scott E. Wenderfer, L. Johnstone, N. Larkins, William K Wong, Agnes A. Alba, T. Ha, Masoumeh Mokham, Xuhui Zhong, R. Hamada, K. Iijima, K. Ishikura, K. Nozu, N. Bresolin, Nilka De Jesus Gonzalez, J. Restrepo, I. Anochie, M. McCulloch   +53 more
semanticscholar   +1 more source

Use of Rituximab in Childhood Idiopathic Nephrotic Syndrome.

American Society of Nephrology. Clinical Journal, 2022
Rituximab is an established therapy in children with idiopathic nephrotic syndrome to sustain short to medium term disease remission and avoid steroid toxicities.
E. Chan, D. Yap, M. Colucci, A. Ma, R. Parekh, K. Tullus   +5 more
semanticscholar   +1 more source

The Immune System and Idiopathic Nephrotic Syndrome.

American Society of Nephrology. Clinical Journal, 2022
Idiopathic nephrotic syndrome often responds to immunosuppressive treatment. Nevertheless, this syndrome - and the drugs used to treat it - remain important causes of patient morbidity.
R. Campbell, J. Thurman
semanticscholar   +1 more source

Molecular factors predicting steroid resistance in pediatric nephrotic syndrome

Український Журнал Нефрології та Діалізу, 2021
Objectives: the objective of this paper was to study the levels of cellular hypoxia, apoptosis controlling factors in children with steroid-sensitive and steroid-resistant nephrotic syndrome.
Ie. A. Burlaka, I. V. Bagdasarova
doaj   +1 more source

Sex and kidney ACE2 expression in primary focal segmental glomerulosclerosis: A NEPTUNE study.

PLoS ONE, 2021
BackgroundAngiotensin-converting enzyme 2 (ACE2) has been implicated in the pathogenesis of experimental kidney disease. ACE2 is on the X chromosome, and in mice, deletion of ACE2 leads to the development of focal segmental glomerulosclerosis (FSGS). The
Nicholas A Maksimowski, James W Scholey, Vanessa R Williams, Nephrotic Syndrome Study Network (NEPTUNE)   +3 more
doaj   +1 more source