Results 41 to 50 of about 60,277 (228)

Protein binding assessment of immobilized nanobody using interferometric nanoporous platform

VIEW, EarlyView.
Nanoporous anodic alumina photonic chip technology is combined with tailor‐engineered “nanobodies”—recombinant variable domains of heavy‐chain‐only antibodies—to achieve high affinity binding to human serum albumin. Abstract Protein sensors are key tools for infectious disease diagnosis and monitoring.
Cheryl Suwen Law, Jayden Revink, Joel Lee, Juan Wang, Andrew D. Abell, Fiona Whelan, Abel Santos   +6 more
wiley   +1 more source

CLINICAL SPECTRUM AND PREDICTIVE RISK FACTORS FOR INFECTIONS IN CHIL-DREN WITH NEPHROTIC SYNDROME

National Journal of Medical Research, 2021
Introduction: Our study aimed to study the incidence of major infections in nephrotic syndrome & the risk factors for major infections & their etiological spectrum. Methods: This was an observational study to find out the incidence of major infection
Ajay D Sethi, Vasav D Desai, Mital M Gover   +2 more
doaj  

The Cost of Love: Emotional Labour and Moral Tensions in the Lives of Chinese Young Carers

The British Journal of Sociology, EarlyView.
ABSTRACT Like adults, children also provide care. This article explores the emotional labour of young carers who care for ill or disabled family members in China, a context where children's caregiving remains largely invisible in both policy and scholarship.
Kefan Xue, Kaidong Guo
wiley   +1 more source

Comprehensive Quantification of Oligoasthenozoospermia Induced by Obesity, Reproductive Toxicants, and Their Combination in Rat Models

Andrology, EarlyView.
ABSTRACT Background Oligoasthenozoospermia is a leading cause of male infertility and has been increasingly associated with the global surge in obesity and exposure to reproductive toxicants. Despite extensive research on each factor individually, their combined pathological effects remain poorly understood.
Yunlong Yao, Xi Zhang, Lingru Li, Yunzhi Zhang, Shuo Huang, Yulin Zong, Mingrui Li, Fufangyu Zhao, Linghui Zhu, Tianxing Li, Wenlong Sun, Mingyan Shao, Yanfei Zheng   +12 more
wiley   +1 more source

The Diagnostic Journey of Childhood Idiopathic Nephrotic Syndrome: Perspectives of Children and Their Caregivers

Canadian Journal of Kidney Health and Disease, 2022
Background: Childhood nephrotic syndrome is a rare kidney disease characterized by sudden onset of edema, massive proteinuria, and hypoalbuminemia. Rare diseases can have a long and difficult trajectory to diagnosis.
Augustina Okpere MBBS, MSc, Susan Samuel MD, MSc, Kathryn King-Shier RN, PhD, Lorraine Hamiwka MD, Meghan J. Elliott MD, MSc   +4 more
doaj   +1 more source

Review of the role of rituximab in the management of adult minimal change disease and immune-mediated focal and segmental glomerulosclerosis

Glomerular Diseases, 2023
Background: Minimal change disease and primary FSGS are podocytopathies but are also immune-mediated diseases. Rituximab acts via multiple mechanisms by tilting the balance between autoreactive B & T cells in favor of regulatory B & T cells.
Ahsan Aslam, Abbal Koirala
doaj   +1 more source

Bleeding Disorders in Children With Genetic Diseases: A Narrative Review

Acta Paediatrica, EarlyView.
ABSTRACT Aim The lack of data on bleeding risk assessment in children with genetic diseases is concerning given their increased care needs and risk of haemorrhagic complications compared to the general population. Identification of haemostatic disorders is crucial for implementing preventive measures and mitigating bleeding risk.
Raphaelle Cagol, Mariam Sbeity Barakat, Marjolaine Willems, Tasnime Akbaraly, Biron‐Andreani Christine, Isabelle Diaz, Alexandre Theron   +6 more
wiley   +1 more source

Effect of empagliflozin on urinary albumin excretion and hypoxic biomarkers in early diabetic kidney disease: A randomised double‐blind, placebo‐controlled trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The precise mechanism of sodium glucose co‐transporter 2 (SGLT2) inhibitor on reno‐protective effect has been still unclear. In this study, we hypothesised that SGLT2 inhibitor prevents diabetic kidney disease via reduction of hypoxia‐induced factors.
Hisashi Makino, Masato Kasahara, Ryuzo Takashima, Shu Kasama, Naoki Ozu, Hyohun Park, Qingxing Chen, Kazuhiko Tsuruya, Mayu Tochiya, Yoko Omura‐Ohata, Tamiko Tamanaha, Michio Noguchi, Takeshi Aiba, Fumiki Yoshihara, Kiminori Hosoda   +14 more
wiley   +1 more source

Postpartum nephrotic syndrome related to new onset of systemic lupus erythematosus: A case report

Case Reports in Women's Health, 2018
Postpartum nephrotic syndrome in a pregnant woman with rheumatoid arthritis in long-standing remission is rare. Systemic lupus erythematosus can remain undiagnosed, especially in the absence of clinical manifestations.
Charalampos Karachalios, Panagiotis Bakas, Anastasia Beta, Efthimios Deligeoroglou   +3 more
doaj   +1 more source

Meropenem‐Heparin Lock Therapy for Ochrobactrum intermedium Catheter‐Related Bloodstream Infection in a Pediatric Hemodialysis Patient: A Case Report and Literature Review

Hemodialysis International, EarlyView.
ABSTRACT Background In pediatric hemodialysis patients with exhausted vascular access, managing rare pathogens like Ochrobactrum intermedium is challenging, often posing a dilemma between catheter removal and salvage attempts. There are few reports on the supported viability of meropenem‐heparin lock therapy for this purpose in pediatric patients. Case
Mônica Cristina Dutra Rodrigues, Fernanda Teixeira Sillva, Anderson Pereira de Oliveira, Yeo Jim Kinoshita Moon, Jhohann Richard de Lima Benzi   +4 more
wiley   +1 more source