Results 51 to 60 of about 92,208 (259)

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

Andrology, EarlyView.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell, Sophia Rahimi, Sherri Lee Jones, Donovan Chan, Josée Martel, Sara Abdessamie, Catherine M. Herba, Jean R. Séguin, William D. Fraser, Celia M. T. Greenwood, Tuong‐Vi Nguyen, Tina C. Montreuil, Jacquetta Trasler   +12 more
wiley   +1 more source

Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B-2 kinin receptors [PDF]

, 2002
Background/Aim: Patients with idiopathic focal segmental glomerulosclerosis (FSGS) often develop a recurrence of the disease after kidney transplantation.
Fink, E., Fischer, K. G., Henger, A., Huber, T. B., Pavenstadt, H., Rump, L. C., Schwertfeger, E.   +6 more
core   +1 more source

Membranoproliferative glomerulonephritis in patients with chronic venous catheters: a case report and literature review. [PDF]

, 2014
Chronic indwelling catheters have been reported to be associated with membranoproliferative glomerulonephritis (MPGN) via the activation of the classical complement pathway in association with bacterial infections such as coagulase negative ...
Nast, Cynthia C, Pham, Phuong-Chi T, Pham, Phuong-Thu T, Sy, John   +3 more
core   +2 more sources

The Diagnostic Journey of Childhood Idiopathic Nephrotic Syndrome: Perspectives of Children and Their Caregivers

Canadian Journal of Kidney Health and Disease, 2022
Background: Childhood nephrotic syndrome is a rare kidney disease characterized by sudden onset of edema, massive proteinuria, and hypoalbuminemia. Rare diseases can have a long and difficult trajectory to diagnosis.
Augustina Okpere MBBS, MSc, Susan Samuel MD, MSc, Kathryn King-Shier RN, PhD, Lorraine Hamiwka MD, Meghan J. Elliott MD, MSc   +4 more
doaj   +1 more source

Coagulopathy in the nephrotic syndrome

Saudi Journal of Kidney Diseases and Transplantation, 2020
Coagulopathy in the nephrotic syndrome (NS) is very rare. Simultaneous prolongation of both prothrombin time and activated partial thromboplastin time suggests common coagulation pathway abnormality such as liver dysfunction, Vitamin K deficiency, disseminated intravascular coagulation, or primary fibrinolysis.
Sneha P Simon, Jose Thomas
openaire   +3 more sources

Efficacy of ciclosporin monotherapy in non‐severe aplastic anaemia not requiring transfusions: Results from a multicentre phase II study

British Journal of Haematology, EarlyView.
Summary The efficacy of ciclosporin (CsA) to treat transfusion‐independent non‐severe aplastic anaemia (TI‐NSAA) has not yet been systematically evaluated. We conducted a prospective trial in patients with TI‐NSAA treated with CsA monotherapy. CsA (3.5 mg/kg/day) was administered to patients with TI‐NSAA aged ≥16.
Ken Ishiyama, Masahide Yamazaki, Hiroyuki Maruyama, Naoko Hosono, Hiroki Yamaguchi, Noboru Asada, Kazuki Tanimoto, Hiroyuki Sugiura, Kensuke Usuki, Kenichi Yoshimura, Seishi Ogawa, Yuzuru Kanakura, Itaru Matsumura, Koichi Akashi, Shinji Nakao   +14 more
wiley   +1 more source

Significance of Exogenous Estradiol on Plasma Cortisol and Salivary Cortisol During Adrenocorticotropic Hormone Stimulation in Women With Pituitary Insufficiency

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Oral estrogens increase the levels of cortisol binding globulin (CBG) potentially affecting test results for adrenal insufficiency. The objective was to evaluate the influence of oral and transdermal estradiol on total plasma (p) and salivary cortisol in hypogonadal women with secondary adrenal insufficiency or at risk of developing ...
Laura S. Aagaard, Jesper Krogh, Signe Perlman, Marianne Klose, Mikkel Andreassen   +4 more
wiley   +1 more source

Postpartum nephrotic syndrome related to new onset of systemic lupus erythematosus: A case report

Case Reports in Women's Health, 2018
Postpartum nephrotic syndrome in a pregnant woman with rheumatoid arthritis in long-standing remission is rare. Systemic lupus erythematosus can remain undiagnosed, especially in the absence of clinical manifestations.
Charalampos Karachalios, Panagiotis Bakas, Anastasia Beta, Efthimios Deligeoroglou   +3 more
doaj   +1 more source

Congenital nephrotic syndrome [PDF]

Pediatric Nephrology, 2007
Abstract Congenital nephrotic syndrome (CNS) is a rare kidney disorder characterized by heavy proteinuria, hypoproteinemia, and edema starting soon after birth. The majority of cases are caused by genetic defects in the components of the glomerular filtration barrier, especially nephrin and podocin.
openaire   +3 more sources

Central nervous system involvement in cardiac amyloidosis: Redefining the heart‐brain axis

European Journal of Clinical Investigation, EarlyView.
Central nervous system involvement in cardiac amyloidosis. Amyloidosis is a systemic disease that can directly affect the central nervous system. Furthermore, the amyloid cardiomyopathy can indirectly affect the central nervous system by inducing systemic hypoperfusion and increasing the risk of acute ischaemic stroke.
Domenico Mario Giamundo, Giuliano Cassataro, Stefano Ministrini, Simon F. Stämpfli   +3 more
wiley   +1 more source