Results 51 to 60 of about 2,325,322 (314)

Emerging Role of SH3BP2 as Regulator of Immune and Nonimmune Cells in Nephrotic Syndrome

Glomerular Diseases
Background: Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are major forms of nephrotic syndrome that remain difficult to treat. MCD and FSGS have distinct but also overlapping clinical, histological, metabolic, and
Tarak Srivastava, Mukut Sharma
doaj   +1 more source

Emerging Role of Myeloperoxidase in the Prognosis of Nephrotic Syndrome Patients Before and After Steroid Therapy [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Myeloperoxidase (MPO) is a myelocyte derived iron containing enzyme particularly involved in host defense by destroying foreign micro organisms invading the body. Numerous evidences suggest that MPO is involved in the pathogenesis of many
Sreelatha Souparnika, Benedicta D’souza, Vivian D’souza, Sushanth Kumar, Poornima Manjrekar, Manohar Bairy, Rajeevalochana Parthasarathy, Srinivas Kosuru   +7 more
doaj   +1 more source

Hydroxychloroquine Associated With Lower Glomerular Filtration Rate Decline in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) protects kidney function in lupus nephritis (LN) by preventing flares, yet some cohort studies show no significant benefit in kidney function with HCQ. Clarifying these conflicting findings by showing early and long‐term benefits of HCQ on kidney function preservation is critical.
Shivani Garg, Brad Rovin, Brad C. Astor, Tripti Singh, Fauzia Hollnagel, Megan Kuik, Lexie Kolton, Callie Saric, S. Sam Lim, Christie M. Bartels   +9 more
wiley   +1 more source

Infantile nephrotic syndrome [PDF]

Postgraduate Medical Journal, 1974
SummaryFour infants, two boys and two girls, with congenital nephrotic syndrome are reported in a single family. The disease process began during the first year of life. The disorder did not respond to corticosteroid therapy. One infant received cyclophosphamide therapy as well without avail. All four children died from intercurrent infection.
N A, Nagi, L, Nouri
openaire   +2 more sources

Long term tapering versus standard prednisolone treatment for first episode of childhood nephrotic syndrome: phase III randomised controlled trial and economic evaluation

British medical journal, 2019
Objective To determine whether extending initial prednisolone treatment from eight to 16 weeks in children with idiopathic steroid sensitive nephrotic syndrome improves the pattern of disease relapse.
N. Webb, R. Woolley, Tosin Lambe, E. Frew, Elizabeth A Brettell, Emma N Barsoum, R. Trompeter, C. Cummins, J. Deeks, K. Wheatley, N. Ives   +10 more
semanticscholar   +1 more source

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng, Dandan Li, Yunyi Li, Chen Yun, Xinzhou Zhang, Wenyu Gong, Mengyun Xiao, Haitao Li, Zhipeng Zeng, Ruqi Tan, Yishen Yang, Shaodong Luan, Yong Dai, Lianghong Yin, Donge Tang   +14 more
wiley   +1 more source

Hubungan Antara Terapi Kortikosteroid Dengan Kejadian Glaukoma Pada Anak Dengan Sindroma Nefrotik [PDF]

, 2012
Background: Nephrotic syndrome is one of the most found kidney disease in children and corticosteroids are the primary form of therapy. Corticosteroids can increase intra-ocular pressure, in which increased intra-ocular pressure becomes a major riks ...
Muryawan, H. (Heru), Radityo, A. N. (Adhie), Wahyuni, A. S. (Andi)   +2 more
core  

Rituximab Use in the Management of Childhood Nephrotic Syndrome

Frontiers in Pediatrics, 2019
Childhood nephrotic syndrome is a challenging and often persistent renal disorder, and its incidence varies between different ethnicities and regions.
M. Kallash, W. Smoyer, J. Mahan
semanticscholar   +1 more source

Albuminuria as a diagnostic criterion and a therapeutic target in heart failure and other cardiovascular disease

European Journal of Heart Failure, EarlyView.
The value of uACR. CKD, chronic kidney disease; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; uACR, urine albumin‐to‐creatinine ratio. Abstract The high disease burden and bidirectional relationship of chronic kidney disease (CKD), heart failure (HF) and other cardiovascular disease (CVD) necessitate the need for early ...
Biykem Bozkurt, Patrick Rossignol, Joseph A. Vassalotti   +2 more
wiley   +1 more source

Relapse of nephrotic syndrome with unusual thromboembolic event: A case report

Clinical Case Reports, 2023
Key Clinical Message Most children with nephrotic syndrome heal without any sequelae. However, rare life‐threatening complications such as thromboembolism may occur in pediatric nephrotic syndrome and should be considered in those with a new‐onset ...
Zahra Pournasiri, Seyedeh Masumeh Hashemi, Seyyedeh Narjes Ahmadizadeh, Bahareh Yaghmaei, Mitra Khalili, Azita Behzad, Amirali Soheili, Mahnaz Jamee   +7 more
doaj   +1 more source