Results 321 to 330 of about 121,280 (344)
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Seminars in Nephrology, 2003
After more than 20 years of cyclosporine use its nephrotoxicity remains a significant clinical problem. Cyclosporine-induced renal injury has been described in solid organs recipients and in patients treated for autoimmune diseases. It is manifested in 2 distinct and well characterized forms, acute nephrotoxicity and chronic nephrotoxicity.
Emmanuel A, Burdmann +3 more
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After more than 20 years of cyclosporine use its nephrotoxicity remains a significant clinical problem. Cyclosporine-induced renal injury has been described in solid organs recipients and in patients treated for autoimmune diseases. It is manifested in 2 distinct and well characterized forms, acute nephrotoxicity and chronic nephrotoxicity.
Emmanuel A, Burdmann +3 more
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Toxicologic Pathology, 1986
Aminoglycosides are life-saving antibiotics in patients with gram negative sepsis. Renal dysfunction occurs in approximately 10% of all clinical courses of aminoglycosides. Because of close pharmacokinetic and toxicologic similarities, rats are excellent human surrogates for comparing the nephrotoxic potentials of these antibiotics. Comparisons in rats
G H, Hottendorf, P D, Williams
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Aminoglycosides are life-saving antibiotics in patients with gram negative sepsis. Renal dysfunction occurs in approximately 10% of all clinical courses of aminoglycosides. Because of close pharmacokinetic and toxicologic similarities, rats are excellent human surrogates for comparing the nephrotoxic potentials of these antibiotics. Comparisons in rats
G H, Hottendorf, P D, Williams
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Drug Intelligence & Clinical Pharmacy, 1982
Lithium-induced nephrotoxicity was first predicted in laboratory animals more than 30 years ago. Evidence in humans, however, did not begin to accumulate until the 1970s. By 1977, anecdotal information was available to suggest that lithium intoxication was not necessarily a prerequisite for the development of nephrotoxicity and that renal damage also ...
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Lithium-induced nephrotoxicity was first predicted in laboratory animals more than 30 years ago. Evidence in humans, however, did not begin to accumulate until the 1970s. By 1977, anecdotal information was available to suggest that lithium intoxication was not necessarily a prerequisite for the development of nephrotoxicity and that renal damage also ...
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The American Journal of Medicine, 1978
Platinum coordination complexes have recently been introduced in cancer chemotherapy with considerable success. However, significant nephrotoxicity has emerged as a factor that limits the therapeutic usefulness of these compounds. In this article we review the available knowledge on platinum nephrotoxicity and its prevention that has been derived from ...
N E, Madias, J T, Harrington
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Platinum coordination complexes have recently been introduced in cancer chemotherapy with considerable success. However, significant nephrotoxicity has emerged as a factor that limits the therapeutic usefulness of these compounds. In this article we review the available knowledge on platinum nephrotoxicity and its prevention that has been derived from ...
N E, Madias, J T, Harrington
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Advances in Chronic Kidney Disease, 2006
Calcineurin inhibitors, cyclosporine and tacrolimus, have improved allograft survival in solid organ transplantation. Indeed, they have reduced the incidence of acute rejection episodes of cadaveric allograft recipients. Although marked progression has been made in initial survival rates, long-term kidney graft survival has yet to show such encouraging
David, Williams, Lukas, Haragsim
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Calcineurin inhibitors, cyclosporine and tacrolimus, have improved allograft survival in solid organ transplantation. Indeed, they have reduced the incidence of acute rejection episodes of cadaveric allograft recipients. Although marked progression has been made in initial survival rates, long-term kidney graft survival has yet to show such encouraging
David, Williams, Lukas, Haragsim
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Journal of Urology, 1992
Investigation of fetal nephrotoxicity by maternally administered nephrotoxins is hampered by many constraints, including the maternal effects of the nephrotoxin, the ability of the nephrotoxin to cross the placenta and the difficulties associated with direct fetal intervention.
G, Steinhardt +3 more
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Investigation of fetal nephrotoxicity by maternally administered nephrotoxins is hampered by many constraints, including the maternal effects of the nephrotoxin, the ability of the nephrotoxin to cross the placenta and the difficulties associated with direct fetal intervention.
G, Steinhardt +3 more
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The American Journal of Medicine, 1990
The high incidence of associated nephrotoxicity represents an important concern in the use of aminoglycoside antibiotics, which have been implicated as one of the primary causes of drug-induced acute renal failure. Several factors, including the underlying health of the patient, criteria used to define nephrotoxicity, and the specific aminoglycoside ...
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The high incidence of associated nephrotoxicity represents an important concern in the use of aminoglycoside antibiotics, which have been implicated as one of the primary causes of drug-induced acute renal failure. Several factors, including the underlying health of the patient, criteria used to define nephrotoxicity, and the specific aminoglycoside ...
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International Urology and Nephrology, 1971
S, Csata, F, Gallyas, D, Frang, M, Tóth
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S, Csata, F, Gallyas, D, Frang, M, Tóth
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