Results 61 to 70 of about 111,114 (198)

Risk factors for cisplatin-induced nephrotoxicity and potential of magnesium supplementation for renal protection. [PDF]

PLoS ONE, 2014
Nephrotoxicity remains a problem for patients who receive cisplatin chemotherapy. We retrospectively evaluated potential risk factors for cisplatin-induced nephrotoxicity as well as the potential impact of intravenous magnesium supplementation on such ...
Yasuhiro Kidera, Hisato Kawakami, Tsutomu Sakiyama, Kunio Okamoto, Kaoru Tanaka, Masayuki Takeda, Hiroyasu Kaneda, Shin-ichi Nishina, Junji Tsurutani, Kimiko Fujiwara, Morihiro Nomura, Yuzuru Yamazoe, Yasutaka Chiba, Shozo Nishida, Takao Tamura, Kazuhiko Nakagawa   +15 more
doaj   +1 more source

Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review

Frontiers in Pharmacology, 2018
Background: Nephrotoxicity is a notable adverse effect in cisplatin treated patients characterized by tubular injury and/or increased serum creatinine (SCr) with incidence varying from 20 to 70%.
Zulfan Zazuli, Zulfan Zazuli, Susanne Vijverberg, Elise Slob, Geoffrey Liu, Geoffrey Liu, Bruce Carleton, Bruce Carleton, Bruce Carleton, Joris Veltman, Paul Baas, Paul Baas, Rosalinde Masereeuw, Anke-Hilse Maitland-van der Zee   +13 more
doaj   +1 more source

Nephrotoxicity and ototoxic symptoms of injectable second-line anti-tubercular drugs among patients treated for MDR-TB in Ethiopia: a retrospective cohort study

BMC Pharmacology and Toxicology, 2019
Background Nephrotoxicity and ototoxicity are clinically significant dose-related adverse effects associated with second-line anti-tubercular injectables drugs (aminoglycosides and capreomycin) used during intensive phase of treatment of multi-drug ...
Workineh Shibeshi, Anandi N. Sheth, Addisu Admasu, Alemseged Beyene Berha, Zenebe Negash, Getnet Yimer   +5 more
doaj   +1 more source

Omeprazole Alleviates Aristolochia manshuriensis Kom-Induced Acute Nephrotoxicity. [PDF]

PLoS ONE, 2016
Aristolochia manshuriensis Kom (AMK) is a member of the Aristolochiaceae family and is a well-known cause of aristolochic acid (AA) nephropathy. In this study, we investigated the potential of omeprazole (OM) to alleviate AMK-induced nephrotoxicity.
Lianmei Wang, Hongbing Zhang, Chunying Li, Yan Yi, Jing Liu, Yong Zhao, Jingzhuo Tian, Yushi Zhang, Xiaolu Wei, Yue Gao, Aihua Liang   +10 more
doaj   +1 more source

Prevalence and Risk Factors of Nephrotoxicity Among Adult Cancer Patients at Mbarara Regional Referral Hospital

Cancer Management and Research, 2021
John Isiiko,1– 3 Barnabas Atwiine,4 Joseph Oloro5 1Department of Pharmacy, Mbarara University of Science and Technology, Mbarara, Uganda; 2Pharmacy Biotechnology and Traditional Medicine Center, Mbarara University of Science and Technology, Mbarara ...
Isiiko J, Atwiine B, Oloro J
doaj  

Overview of Antibiotic-Induced Nephrotoxicity

Kidney International Reports, 2023
R. E. Campbell, C. Chen, C. Edelstein
semanticscholar   +1 more source

The Renin-Angiotensin System Involvement in Cisplatin-Induced Nephrotoxicity: An Overview of Physiological and Pathological Mechanisms—A Systematic Review

International Journal of Nephrology
Cisplatin (CDDP) is a highly potent chemotherapy drug. But its nephrotoxicity poses a significant limitation to its use. The renin-angiotensin system (RAS) has been proposed to play a role in drug-induced nephrotoxicity.
Aryan Vakilian, Sina Mohammadi, Fatemeh Shokri, Maryam Maleki, Maryam Kheiry, Amin Kheiri   +5 more
doaj   +1 more source

Nephrotoxicity of Cancer Immunotherapies: Past, Present and Future.

Journal of the American Society of Nephrology, 2018
Nephrotoxicity from cancer therapies is common and increasingly encountered in clinical practice, such that the subfield of "onco-nephrology" has emerged.
M. Perazella, A. Shirali
semanticscholar   +1 more source

Astragaloside IV alleviates cisplatin-induced nephrotoxicity in Lewis lung carcinoma mice and inhibits the epithelial-mesenchymal transition-mediated invasion and metastasis of lung cancer cells [PDF]

, 2022
Xue Han, Zhi qiang Hu, Han Chen, Ke Wang, Xiao juan Gao, Fengmei Li, Jing Wang   +6 more
openalex   +1 more source

Nephrotoxicity and Renal Pathophysiology: A Contemporary Perspective

Toxicological Sciences, 2018
The kidney consists of numerous cell types organized into the nephron, which is the basic functional unit of the kidney. Any stimuli that induce loss of these cells can induce kidney damage and renal failure.
L. Barnett, B. Cummings
semanticscholar   +1 more source