Results 141 to 150 of about 446,801 (290)

Hyperactive KIF5A in Neurodegeneration

open access: yesCytoskeleton, EarlyView.
ABSTRACT The highly polarised morphology of neurons and the sheer length of their axons make transport of cargoes throughout the cell a formidable task. Decades of evidence obtained from genetic studies on patients and animal models highlight deficits in axonal transport as a recurrent cause, or early contributing factor, in a plethora of ...
David Villarroel‐Campos   +1 more
wiley   +1 more source

Tramadol Co‐Administration with Oxycodone or Hydrocodone Increases Opioid Burden without Improving Postoperative Pain Control

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Tramadol is frequently co‐prescribed with oxycodone or hydrocodone after surgery under the assumption that its dual mechanism of action provides an opioid‐sparing benefit. However, evidence supporting this practice is limited and inconsistent. We conducted a secondary analysis of the multicenter IGNITE ADOPT‐PGx pragmatic trial of patients undergoing ...
Noor A. Nahid   +302 more
wiley   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai   +12 more
wiley   +1 more source

Does EU Taxonomy Alignment Reduce Corporate Emissions? Evidence From Nordic Firms

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This paper investigates whether EU Taxonomy alignment is associated with lower corporate emissions, using 982 firm‐years from 358 Nordic firms (2022–2025). Extending targeted transparency theory, the study develops a signal‐quality framework under which a mandated classification is informative only if it satisfies signal relevance, signal ...
Ane C. H. Jensen
wiley   +1 more source

Evidence for functional convergence between LZTS2 and DYRK1A during craniofacial development

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Precise control of DYRK1A dosage is essential for embryonic development, including craniofacial morphogenesis. While LZTS2 is among the most consistently identified DYRK1A‐interacting proteins, its roles in embryonic development remain incompletely understood, and its potential contribution to craniofacial development has not been ...
Nicole Cheng   +3 more
wiley   +1 more source

Niobium‐Based Chalcogenides as Emerging Electrode Materials for Rechargeable Batteries

open access: yesEcoEnergy, EarlyView.
This review highlights recent advances in Nb‐based TMCs, covering their structure‐property relationships, synthesis strategies, electrochemical mechanisms, and energy‐storage applications. Emerging approaches including defect engineering, operando characterization, DFT modeling, and AI‐assisted design are discussed to accelerate the development of high‐
Narasimharao Kitchamsetti   +3 more
wiley   +1 more source

The role of the prostatic vasculature as an intraoperative landmark for nerve sparing during robot assisted radical prostatectomy

open access: yes, 2011
The role of the prostatic vasculature as an intraoperative landmark for nerve sparing during robot assisted radical ...
Chauhan S   +10 more
core  

Intraoperative Techniques Aiding Margin Assessment and Nerve Sparing During Robot-Assisted Radical Prostatectomy. [PDF]

open access: yesCancers (Basel)
Kisiała M   +14 more
europepmc   +1 more source

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