Results 221 to 230 of about 446,801 (290)

Efficacy and safety of male fertility-sparing radical cystectomy with orthotopic neobladder versus radical cystectomy and nerve-sparing cystectomy: a meta-analysis. [PDF]

Front Oncol
Huang Y, Shi H, Wang Q, Wang Z, Wang R, Zhang Y, Wang J, Zhang N, Fu S, Wang H.   +9 more
europepmc   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Comparative Analysis of Cold Versus Thermal Dissection in Nerve-Sparing Robot-Assisted Radical Prostatectomy. [PDF]

Cancers (Basel)
Fuschi A, Sequi MB, Al Salhi Y, Suraci PP, Valenzi FM, Rera OA, Antonioni A, Graziani D, Martino G, Candita G, Gianfrancesco F, Benanti P, Erra L, Di Gregorio G, Lombardo R, Asimakopoulos AD, De Nunzio C, Crocetto F, Pacini M, Sollazzi E, Zucchi A, Carbone A, Pastore AL.   +22 more
europepmc   +1 more source

What Is the Role of Uvulopalatopharyngoplasty in Contemporary Sleep Surgery?

The Laryngoscope, EarlyView.
Thomas M. Kaffenberger, Megan Durr, Ryan Soose, Patrick J. Strollo, Jolie L. Chang   +4 more
wiley   +1 more source

Aptamer–Based Targeted Protein Degradation: Mechanistic Principles, Delivery Strategies, and Translational Opportunities

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted elimination of pathogenic proteins remains a fundamental challenge in therapeutic intervention, particularly for proteins considered “undruggable” by conventional inhibition‐based approaches. Aptamer–based targeted protein degradation (TPD) has emerged as a versatile strategy that leverages the high specificity, structural ...
Ambrin Malik, Suyeon Son, Jaesung Lee, Ki Soo Park   +3 more
wiley   +1 more source

Comparative Outcomes of Laparoscopic Radical Hysterectomy and Nerve-Sparing Technique in Cervical Cancer Patients. [PDF]

JSLS
Puntambekar S, Parulekar M, Venkateswaran S, Naidu S, Patil M, Manerikar K, Bharambe S, Chitale M, Panse M, Sathe R, Puntambekar S.   +10 more
europepmc   +1 more source

Neurological Adverse Effects Associated With Commonly Used H1‐Antihistamines: A Narrative Review of Age‐Stratified Risk Profiles in Paediatric and Geriatric Populations

Medicine Advances, EarlyView.
This narrative review examines the neurological adverse effects associated with commonly used H1‐antihistamines, focusing on how blood–brain barrier (BBB) penetration and patient age influence central nervous system (CNS) toxicity. The major finding is that first‐generation antihistamines, because of higher CNS penetration, are associated with ...
Syeda Samia Fatima, Zahabia Adnan, Rabia Nizam, Marium Fawad, Zainab Mehmood, Areeba Asif, Ali Aamir   +6 more
wiley   +1 more source

Predictors of corporo-venocclusive dysfunction in men with bilateral nerve-sparing radical prostatectomy. [PDF]

J Sex Med
Flores JM, Novaes LF, Vertosick E, Salter C, Liso N, Vickers AJ, Mulhall JP, Fecsm.   +7 more
europepmc   +1 more source