Results 71 to 80 of about 4,888,974 (334)
Interactions of cyclodextrins and their derivatives with toxic organophosphorus compounds
Beilstein Journal of Organic Chemistry, 2016 The aim of this review is to provide an update on the current use of cyclodextrins against organophosphorus compound intoxications. Organophosphorus pesticides and nerve agents play a determinant role in the inhibition of cholinesterases.
Sophie Letort +4 more
doaj +1 more source
Topical treatment of peripheral neuropathic pain: applying the evidence [PDF]
, 2017 Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events.
Cruccu, Giorgio, Sommer, Claudia
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Exploiting macrocyclic polylactam for sensing V-series nerve agents: A computational study
Results in ChemistryThe nerve agents are organophosphorus compounds (OPs) developed as chemical warfare agents (CWAs) that inhibit acetylcholinesterase (AChE) and lead to impeding neurological signals in mammals.
Dipankar Das, Bishwajit Ganguly
doaj +1 more source
Chemical Weapons: History of the Study of Organophosphorus Toxic Agents Abroad
Вестник войск РХБ защиты, 2023 Organophosphorus compounds occupy a unique positon among all chemical warfare agents (CWA's). Since the 1930-s their high toxicity, wide range of physical-chemical properties and complex action attracted close attention of foreign military experts.
I. A. Nelga +5 more
doaj +1 more source
Is there a "safety zone" in the mandibular premolar region where damage to the mental nerve can be avoided if periapical extrusion occurs? [PDF]
, 2010 The mandibular premolars are located close to the mental foramina (Fig. 1). As such, various events affecting these teeth, such as odontogenic infection1 and orthodontic, endodontic, periodontal or surgical misadventure, may result in neurosensory ...
Ngeow, Dr. W.C.
core +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Investigating possibilities and recent trends for the development of novel decontamination technologies [PDF]
Scientific Technical ReviewDespite international prohibition of chemical warfare agents (CWAs), defined in Chemical Weapons Convention, recent events during military conflict in Syria and isolated events in Salisbury (UK) and Kuala Lumpur (Malesya) airport prove that these agents ...
Vitorović-Todorović Maja D. +1 more
doaj +1 more source
Cumhuriyet Science Journal, 2020 In this study, a carboxymethyldextran chip based sensor system is developed that selectively recognizes and binds nerve agent molecules used in chemical weapons. Nerve agents fall under the group of organophosphorus compounds and irreversibly inhibit the
Ozan Yağmuroğlu, Sibel Emir Diltemiz
doaj +1 more source
Activity of Cyclic AMP Phosphodiesterases and Adenylyl Cyclase in Peripheral Nerve after Crush and Permanent Transection Injuries [PDF]
, 1998 Recent studies demonstrate that cAMP levels are tightly controlled during demyelination and remyelination in Schwann cells as cAMP decreases to 8–10% of normal following both sciatic nerve crush or permanent transection injury and only begins to increase
Poduslo, Joseph F. +1 more
core +1 more source