Results 81 to 90 of about 12,921,549 (290)

Relationship between nerve ultrasonography image and electrophysiology in diabetic polyneuropathy

open access: yesJournal of Diabetes Investigation
Aims/Introduction This study aims to investigate the association between cross‐sectional area (CSA) imaging findings of nerve ultrasound and conventional nerve conduction studies (NCS) for patients with distal symmetric sensorimotor polyneuropathy (DSPN)
Pei‐Chen Hsieh   +5 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

The Relationship between Nerve Conduction Studies and Electromyography Findings in Patients with Carpal Tunnel Syndrome

open access: yesCaspian Journal of Neurological Sciences, 2016
Background: Carpal tunnel syndrome is the most common neuropathy in the general population. Nerve conduction studies are among the standard methods for diagnosing carpal tunnel syndrome. Electromyography is painful and unpleasant, and if nerve conduction
Parisa Maddahian-Najafabadi   +4 more
doaj  

Cardio-Ankle Vascular Index and Indices of Diabetic Polyneuropathy in Patients with Type 2 Diabetes

open access: yesJournal of Diabetes Research, 2017
The cardio-ankle vascular index (CAVI) is used to test vascular function and is an arterial stiffness marker and potential predictor of cardiovascular events.
Akihiko Ando   +5 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]

open access: yes, 1993
Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Niedermeier, W.   +2 more
core   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec   +6 more
wiley   +1 more source

Clinico-Radiological Correlation in Carpal Tunnel Syndrome: Evaluating the Efficacy of Shear Wave Elastography and Nerve Conduction Studies

open access: yesNational Board of Examinations Journal of Medical Sciences
Introduction: Carpal Tunnel Syndrome (CTS) is a prevalent peripheral entrapment neuropathy caused by the compression of the median nerve at the wrist, leading to symptoms such as intermittent paraesthesia, pain, and muscle weakness. The condition is more
Rajiv Sathianarayanan Menon   +4 more
doaj   +1 more source

Preliminary Study on the Lesion Location and Prognosis of Cubital Tunnel Syndrome by Motor Nerve Conduction Studies

open access: yesChinese Medical Journal, 2015
Background: To study lesions′ location and prognosis of cubital tunnel syndrome (CubTS) by routine motor nerve conduction studies (MNCSs) and short-segment nerve conduction studies (SSNCSs, inching test).
Zhu Liu   +4 more
doaj   +1 more source

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