Results 51 to 60 of about 120,431 (347)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Clinical and neurophysiological correlation in axonal and demyelinating polyneuropathy

Bulletin of the National Research Centre, 2020
Background The neurophysiological examination provides valuable pathophysiological information for the diagnosis, prognosis, and therapy of patients with polyneuropathy (Fuglsang- Fredriksen A., Pugdahl K. Clin Neurophysilogy 122:440–455, 2011).
Kamel Mahmoud Ali Hewedi, Mahmoud Abdelmoety Monzer, Khaled Mohammad Sobh, Mohammad Abdelhady M. Aboelmakarem, Amir Abdelghaffar Mohammady, Mahmoud Mohamad Hasan, Mohammad Fathi Abdulsalam, Suzette Ibrahim Ibrahim Ibrahim Helal   +7 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Genetic analysis of peripheral nerve conduction velocity in twins [PDF]

, 1995
We studied variation in peripheral nerve conduction velocity (PNCV) and intelligence in a group of 16-year-old Dutch twins. It has been suggested that both brain nerve conduction velocity and PNCV are positively correlated with intelligence (Reed, 1984 ...
D. I. Boomsma, D. I. Boomsma, D. I. Boomsma, D. M. Ma, D. N. Jackson, D. S. Stetson, E. Chourchesne, F. V. Rijsdijk, J. C. Raven, J. C. Wickett, J. E. Desmedt, J. P. Hegmann, J. P. Hegmann, J. R. Koopmans, J. R. Koopmans, J. Risberg, K. G. Jöreskog, M. C. Neale, M. E. Phelps, M. Neale, P. A. Vernon, P. A. Vernon, P. A. Vernon, P. A. Vernon, P. T. Barrett, R. Plomin, R. Plomin, S. J. Oh, T. E. Reed, T. E. Reed, T. E. Reed, T. E. Reed, T. J. Bouchard, T. N. Chase   +33 more
core   +2 more sources

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Correlates of calcaneal quantitative ultrasound parameters in patients with diabetes: the study on the assessment of determinants of muscle and bone strength abnormalities in diabetes [PDF]

, 2017
OBJECTIVE: Quantitative ultrasound (QUS) provides an estimate of bone mineral density (BMD) and also evaluates bone quality, which has been related to increased fracture risk in people with diabetes.
Alessi, Elena, Balducci, Stefano, Bollanti, Lucilla, Conti, Francesco, D'Errico, Valeria, Iacobini, Carla, Menini, Stefano, Nicolucci, Antonio, Pugliese, Giuseppe, Pugliese, Luca, Salerno, Gerardo, Vitale, Martina   +11 more
core   +2 more sources

Autosomal Recessive Spastic Ataxia of Charlevoix‐Saguenay in Two Half‐Siblings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Autosomal recessive spastic ataxia of Charlevoix‐Saguenay (ARSACS) is caused by biallelic pathogenic variants in the SACS gene. We report the clinical, radiologic and neurophysiologic features of a pair of half‐siblings who presented with progressive cerebellar ataxia, peripheral neuropathy and upper motor neuron signs.
Dennis Yeow, Matthew Katz, Jonathan Rodgers, Mark Davis, Thomas Robertson, R. J. McKinlay Gardner, Pamela A. McCombe   +6 more
wiley   +1 more source

Effect of Hand Held Vibrating Tools on Nerve Conduction Study in Dental Residents

Journal of Nepal Health Research Council, 2020
Background: Repetitive exposure to vibration has been shown to induce peripheral nerve dysfunction. Dentists are exposed to handheld vibrating tools in their daily clinical practice.
Rekha Limbu, Dilip Thakur, Nirmala Limbu, Prakash Parajuli, Shivalal Sharma, Navin Agrawal, Robin Maskey   +6 more
doaj   +1 more source

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
wiley   +1 more source

Pathological classification of equine recurrent laryngeal neuropathy [PDF]

, 2018
Recurrent Laryngeal Neuropathy (RLN) is a highly prevalent and predominantly left‐sided, degenerative disorder of the recurrent laryngeal nerves (RLn) of tall horses, that causes inspiratory stridor at exercise because of intrinsic laryngeal muscle ...
Draper, A C E, Piercy, R J
core   +2 more sources