Results 221 to 230 of about 183,684 (312)

Electron Microscopic Mapping of Mitochondrial Morphology in the Cochlear Nerve Fibers. [PDF]

J Assoc Res Otolaryngol
Lu Y, Jiang Y, Wang F, Wu H, Hua Y.
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

First Application of Whole Genome Sequencing in Myelinated Retinal Nerve Fibers (MRNF). [PDF]

Physiol Res
Scott Sills E, Harrity C, Chu HI, Wang JW, Wood SH, Tan SL.   +5 more
europepmc   +1 more source

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

Advanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina, Kanghwan Kim, Wesley Charles Smith, Keuntae Kim, Shinwoo Lee, Jiwan Woo, Il‐Joo Cho   +6 more
wiley   +1 more source

Electron Microscopy of Nerve Fibers V. On the Fine Structure of the Small Myelinated Nerve Fibers in the Peripheral Nerve

Okajimas Folia Anatomica Japonica, 1962
Honjin, Ryohei, Takahashi, Akira, Nakamura, Akira, Taniguchi, Hikaru   +3 more
openaire   +3 more sources

Tracing nerve fibers with volume electron microscopy to quantitatively analyze brain connectivity. [PDF]

Commun Biol
Turegano-Lopez M, de Las Pozas F, Santuy A, Rodriguez JR, DeFelipe J, Merchan-Perez A.   +5 more
europepmc   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Characteristics of the fundus and optical coherence tomography angiography metrics in myopic patients with myelinated retinal nerve fibers. [PDF]

BMC Ophthalmol
Yang W, Wei R, Zhang C, Huang C, Lin F, Shen Y, Yang C, Zhou X, Li M.   +8 more
europepmc   +1 more source