Results 31 to 40 of about 166,621 (264)

Lingual innervation in male and female marmosets

Neurobiology of Pain, 2023
Several gaps in knowledge exists in our understanding of orofacial pain. Some of these include type of peripheral sensory innervation in specific tissues, differences in innervation between sexes and validation of rodent studies in higher order species ...
Meilinn Tram, Tarek Ibrahim, Anahit Hovhannisyan, Armen Akopian, Shivani Ruparel   +4 more
doaj   +1 more source

The ansa cervicalis and superior cervical ganglion contribute to the fiber composition of the human hypoglossal nerve and its branches

Scientific Reports
The hypoglossal nerve is considered a pure motor nerve. Yet, there are indications that it contains sensory and sympathetic fibers in the periphery. We analyzed changes in the fiber composition along the human hypoglossal nerve, delineating the pathways ...
Giorgi Didava, Arzu Petersen, Génova Carrero-Rojas, Paata Pruidze, Angel M. Pastor, Wolfgang J. Weninger, Roland Blumer   +6 more
doaj   +1 more source

Site-dependent differences in the composite fibers of male pelvic plexus branches: an immunohistochemical analysis of donated elderly cadavers

BMC Urology, 2018
Background Although the pelvic autonomic plexus branches are considered to be a mixture of sympathetic and parasympathetic nerves, little is known regarding the composite fibers of the pelvic plexus branches.
Kuniyasu Muraoka, Shuichi Morizane, Keisuke Hieda, Masashi Honda, Takehiro Sejima, Gen Murakami, Shin-ichi Abe, Atsushi Takenaka   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Plasticity of Unmyelinated Fibers in a Side-to-end Tubulization Model

Plastic and Reconstructive Surgery, Global Open, 2019
Background:. Histomorphometric studies of unmyelinated fibers of the rat fibular nerves are uncommon, and side-to-end neurorrhaphy studies using the fibular nerve investigate primarily motor fibers.
Vânia Tognon-Miguel, MS, Adriana H. Nascimento-Elias, PhD, Maria C. L. Schiavoni, MS, Amilton A. Barreira, MD, PhD   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Polymeric Fibers as Scaffolds for Spinal Cord Injury: A Systematic Review

Frontiers in Bioengineering and Biotechnology, 2022
Spinal cord injury (SCI) is a complex neurological condition caused by trauma, inflammation, and other diseases, which often leads to permanent changes in strength and sensory function below the injured site. Changes in the microenvironment and secondary
Yuanpei Cheng, Yanbo Zhang, Han Wu
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Crush injury to motor nerves in the G93A transgenic mouse model of amyotrophic lateral sclerosis promotes muscle reinnervation and survival of functionally intact nerve-muscle contacts

Neurobiology of Disease, 2018
Selective survival of small motor nerve fibers and their neuromuscular contacts in the SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis (ALS) suggests that smaller regenerated nerve fibers are more able to sustain reformed nerve-muscle ...
P.S. Sharp, N. Tyreman, K.E. Jones, T. Gordon   +3 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source