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International Journal of Neuroscience, 1985
Nerve growth factor is a polypeptide hormone that is required for the normal growth and development of the embryonic sensory and sympathetic nervous systems. On these cells, there are two different receptors for the nerve growth factor. Recently, these receptors have been isolated from three cell types and shown to have essentially the same binding ...
David J. Ennulat+3 more
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Nerve growth factor is a polypeptide hormone that is required for the normal growth and development of the embryonic sensory and sympathetic nervous systems. On these cells, there are two different receptors for the nerve growth factor. Recently, these receptors have been isolated from three cell types and shown to have essentially the same binding ...
David J. Ennulat+3 more
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NERVE GROWTH FACTOR AND THE SKIN
International Journal of Dermatology, 1994.
PINCELLI, Carlo+2 more
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Nerve growth factor as an angiogenic factor
Microvascular Research, 2008Nerve growth factor (NGF), a neurotrophin that plays a crucial role in promoting neurotrophic and neurotropic effects in sympathetic neurons, has recently been identified as a novel angiogenic molecule, which exerts a variety of effects in the cardiovascular system and on endothelial cells.
BENAGIANO V+4 more
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Growth regulation by nerve growth factor
Molecular and Cellular Biochemistry, 1979Although a great deal of descriptive information has been obtained about the actions of nerve growth factor on its target tissues, its structure, its receptors, and even its biosynthesis, there is no clear understanding, as yet, of the intracellular events mediating its transcriptional involvements.
Takeyuki Ikeno, Gordon Guroff
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chapter 6 Nerve Growth Factors and Control of Nerve Growth
1980Publisher Summary This chapter surveys developmental observations indicating the occurrence of target derived signals that permit a neuron to survive at and beyond a critical time in its life course. It introduces and illustrates the concepts of a trophic drive responsible for both survival and growth supportive production, and of specifying ...
Ruben Adler, Silvio Varon
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Nerve Growth Factor, Stress and Diseases
Current Medicinal Chemistry, 2021Stress is a constant threat for homeostasis and is represented by different extrinsic and intrinsic stimuli (stressors, Hans Selye’s "noxious agents"), such as aggressive behavior, fear, diseases, physical activity, drugs, surgical injury, and environmental and physiological changes.
Flavio Maria Ceci+11 more
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Nerve growth factor and nociception
Trends in Neurosciences, 1993Nerve growth factor (NGF) is thought of as a target-derived factor responsible for the survival and maintaining the phenotype of specific sets of peripheral and central neurons during development and maturation. Recently, using physiological techniques, we have shown that specific functional types of nociceptive sensory neurons require NGF, first for ...
Gary R. Lewin, Lorne M. Mendell
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On the immunology of nerve growth factor
Neuroscience Letters, 1985We report some experiments on the immunological properties of nerve growth factor from the venom of Heloderma horridum and from bull seminal vesicles. On the basis of these results, taken together with results already in the literature, we propose an operational definition of the term nerve growth factor.
Charles A. Vernon+3 more
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Trends in Biochemical Sciences, 1993
Recent studies on nerve growth factor have revealed important new insights into the structure, function and evolution of this prototypical neurotrophic factor. Some of its features are (1) it has a unique three-dimensional fold that has since been found in two other growth factors, (2) it uses the trk proto-oncogene product, which has a tyrosine kinase,
Neil Q. McDonald+4 more
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Recent studies on nerve growth factor have revealed important new insights into the structure, function and evolution of this prototypical neurotrophic factor. Some of its features are (1) it has a unique three-dimensional fold that has since been found in two other growth factors, (2) it uses the trk proto-oncogene product, which has a tyrosine kinase,
Neil Q. McDonald+4 more
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Tissue Localization of Nerve Growth Factor and Nerve Growth Factor Receptors
1991The pioneering investigations of Levi-Montalcini and coworkers established that nerve growth factor (NGF) is an important physiological regulator of neurons of the peripheral nervous system. No doubt in part because of the dramatic and specific effects on the sympathetic and sensory nervous system resulting from immunochemically depriving rodents of ...
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