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Receptors for Nerve Growth Factor
1993Publisher Summary This chapter discusses the two receptors for nerve growth factor (NGF)—namely, (1) the low-affinity NGF receptor and (2) the product of the proto-oncogene trk . It also reviews the way they were originally identified and the structural and functional features of the two receptors.
David S. Battleman +2 more
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Biochemistry, 1986
Pheochromocytoma (PC12) cells have been found to differ from dorsal root ganglionic cells with respect to the modulation of the beta nerve growth factor (beta NGF) binding properties elicited by alpha NGF and gamma NGF. In contrast to our previous results with intact dorsal root ganglionic cells in which only high-affinity binding was blocked, alpha ...
Kenneth E. Neet, Nathaniel R. Woodruff
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Pheochromocytoma (PC12) cells have been found to differ from dorsal root ganglionic cells with respect to the modulation of the beta nerve growth factor (beta NGF) binding properties elicited by alpha NGF and gamma NGF. In contrast to our previous results with intact dorsal root ganglionic cells in which only high-affinity binding was blocked, alpha ...
Kenneth E. Neet, Nathaniel R. Woodruff
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1987
Beta-nerve growth factor (s-NGF) is a polypeptide of 118 amino acids, and is a member of the group of polypeptide growth factors (PGF) that includes epidermal growth factor (EGF), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), and several other growth factors (see Table 1).
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Beta-nerve growth factor (s-NGF) is a polypeptide of 118 amino acids, and is a member of the group of polypeptide growth factors (PGF) that includes epidermal growth factor (EGF), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), and several other growth factors (see Table 1).
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1990
The discovery of nerve growth factor (NGF) nearly 4 decades ago and the research that followed have had a profound impact upon our understanding of neurotrophic factors and neuronal survival and development. The requirement of NGF by selective neuronal populations implies that many other neurotrophic factors are functioning in the nervous system.
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The discovery of nerve growth factor (NGF) nearly 4 decades ago and the research that followed have had a profound impact upon our understanding of neurotrophic factors and neuronal survival and development. The requirement of NGF by selective neuronal populations implies that many other neurotrophic factors are functioning in the nervous system.
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Nerve growth factor and the neostriatum
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 19911. The present review summarizes evidence describing the expression, immunoreactivity, binding, transport, development, aging, and functions of NGF in the mammalian neostriatum. 2. Neostriatal NGF binding sites and intrinsic cholinergic neurons are co-localized, increase at a similar rate during ontogeny, and are lost to an equal extent following age ...
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Regulation of the Synthesis of Nerve Growth Factor and Nerve Growth Factor Receptor
1988The importance of Nerve Growth Factor (NGF) for the development and the maintenance of differentiated properties of peripheral sympathetic and neural crest- derived sensory neurons as well as for basal forebrain cholinergic neurons is well established (cf Levi-Montalcini & Angeletti, 1968; Greene & Shooter, 1980; Thoenen & Barde, 1980; Thoenen et al ...
Hans Thoenen +7 more
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Cancer treatment and survivorship statistics, 2022
Ca-A Cancer Journal for Clinicians, 2022Kimberly D Miller +2 more
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