Results 101 to 110 of about 3,082,625 (411)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich +10 more
wiley +1 more source
Frontiers in Physiology, 2019 Skeletal muscle atrophy is associated with pro-inflammatory cytokines. Salidroside is a biologically active ingredient of Rhodiola rosea, which exhibits anti-inflammatory property.
Changyue Wu +9 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source
Flavonoids: a natural remedy in the prevention and management of diverse diseases
Frontiers in MedicineBackgroundFlavonoids, which fall into the polyphenol family as secondary metabolites, can be widely found in traditional Chinese herbal medicines. Owing to their multi-target characteristics, low toxicity levels, and diverse sources, flavonoids have ...
Bo Yu +7 more
doaj +1 more source
Estimations of topographically correct regeneration to nerve branches and skin after peripheral nerve injury and repair. [PDF]
, 2014 Peripheral nerve injury is typically associated with long-term disturbances in sensory localization, despite nerve repair and regeneration. Here, we investigate the extent of correct reinnervation by back-labeling neuronal soma with fluorescent tracers ...
Molander, Carl +2 more
core +2 more sources
Peripheral nerve injury and axonotmesis: State of the art and recent advances
, 2018 Peripheral nerve lesions are frequent occurrences in both human and animal patients, leading to important physiological and labor complications that affect the quality of life of those who suffer the injury. More severe injuries are often associated with
R. Alvites +7 more
semanticscholar +1 more source
Journal of Neuroscience, 2017 Wallerian degeneration (WD) is considered an essential preparatory stage to the process of axonal regeneration. In the peripheral nervous system, infiltrating monocyte-derived macrophages, which use the chemokine receptor CCR2 to gain entry to injured ...
J. Lindborg, M. Mack, R. Zigmond
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aims This study aimed to explore the relationship between stress‐induced hyperglycemia (SIH) and in‐hospital medical complications in patients with acute stroke. Methods We enrolled 865,765 patients with acute stroke from the Chinese Stroke Center Alliance cohort.
Xintong Song +6 more
wiley +1 more source
Loss of neurons from laminas I-III of the spinal dorsal horn is not required for development of tactile allodynia in the spared nerve injury model of neuropathic pain [PDF]
, 2005 It has been proposed that death of inhibitory interneurons in the dorsal horn contributes to the neuropathic pain that follows partial nerve injury. In this study, we have used two approaches to test whether there is neuronal death in the dorsal horn in ...
Arham, A.Z. +3 more
core +2 more sources
The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen +5 more
wiley +1 more source