Results 101 to 110 of about 33,105 (266)

Transcriptional Repression of p53 by PAX3 Contributes to Gliomagenesis and Differentiation of Glioma Stem Cells

open access: yesFrontiers in Molecular Neuroscience, 2018
Although there are available therapies as surgery, chemotherapy and radiation, glioblastoma (GBM) still has been considered as the most common and overwhelming primary tumor of brain. In GBM, the brain glioma stem cells (BGSCs) were identified and played
Hui Zhu   +11 more
doaj   +1 more source

Anatomy of the vertebral column lymphatic network in mice [PDF]

open access: yesarXiv, 2019
Cranial lymphatic vessels (LVs) are involved in transport of fluids, macromolecules and CNS immune responses. Little information about spinal LVs is available, because these delicate structures are embedded within vertebral tissues and difficult to visualize using traditional histology. Here we reveal an extended vertebral column LV network using three-
arxiv  

Supercritical Fluid‐Processed Multifunctional Hybrid Decellularized Extracellular Matrix with Chitosan Hydrogel for Improving Photoaged Dermis Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
These findings advance tissue repair by offering a multifunctional filler that improves large‐scale volume retention, elasticity, and support for vascularized tissue growth. The decellularized extracellular matrix (dECM)‐based material provides low injection force and minimizes swelling, ensuring sustained volume. Combining CMC with supercritical fluid‐
Seol‐Ha Jeong   +6 more
wiley   +1 more source

Soft Pneumatic Device Designed to Mimic the Periosteal Environment for Regulating the Fate of Mesenchymal Stem Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a custom‐made soft pneumatic device (SPD) that mimics complex mechanical forces and fluid flow to enhance in vitro cell differentiation. It shows that low mechanotransduction promotes MSC differentiation into osteoprogenitor cells, while high mechanotransduction causes structural disruptions and cell detachment, providing new ...
Gwang‐Bum Im   +9 more
wiley   +1 more source

Thermally Drawn Shape and Stiffness Programmable Fibers for Medical Devices

open access: yesAdvanced Healthcare Materials, EarlyView.
Thermal drawing technique is adapted to fabricate Shape Memory Polymer Fibers (SMPFs) with programmable stiffness and shape. Multilumen and multimaterial SMPFs are developed for innovative medical devices: stiffness adjustable catheters, body temperature softening neural interfaces, and shape programmable cochlear implants.
Jiwoo Choi   +16 more
wiley   +1 more source

Proximal Planar Cech Nerves. An Approach to Approximating the Shapes of Irregular, Finite, Bounded Planar Regions [PDF]

open access: yesarXiv, 2017
This article introduces proximal Cech nerves and Cech complexes, restricted to finite, bounded regions $K$ of the Euclidean plane. A Cech nerve is a collection of intersecting balls. A Cech complex is a collection of nerves that cover $K$. Cech nerves are proximal, provided the nerves are close to each other, either spatially or descriptively.
arxiv  

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