Results 111 to 120 of about 3,055,547 (410)

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Iatrogenic nerve injuries [PDF]

Postgraduate Medical Journal, 1982
Abstract Thirty-one examples of iatrogenic peripheral nerve injuries have been collected from a review of the case records of one neurological referral centre over a 7-year period. The clinical details are described to call attention to the special care needed with the management of patients subjected to certain invasive procedures.
J. B. Winer, M. J. G. Harrison
openaire   +3 more sources

Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco, Mònica Roldán, Yalda Jamshidi, Ioannis Georvasilis, Rocío Jadraque Rodríguez, Reza Boostani, Ali Shoeibi, Lluís Armengol, Anna Codina, Ehsan Ghayoor Karimiani, Cristina Hernando‐Davalillo, Loreto Martorell, María Luisa Ramírez Almaraz, Jordi Muchart, Carlos Ortez, Andrés Nascimento, Roser Urreizti, Daniel Natera‐de Benito, Mercedes Serrano   +18 more
wiley   +1 more source

Peripheral Nerve Injury: Stem Cell Therapy and Peripheral Nerve Transfer

International Journal of Molecular Sciences, 2016
Peripheral nerve injury can lead to great morbidity in those afflicted, ranging from sensory loss, motor loss, chronic pain, or a combination of deficits.
Robert Sullivan, T. Dailey, K. Duncan, Naomi Abel, C. Borlongan   +4 more
semanticscholar   +1 more source

Coronectomy as a surgical approach to impacted mandibular third molars: A systematic review [PDF]

, 2015
The aim of this systematic review was to evaluate the clinical effectiveness of the surgical technique of coronectomy for third molars extraction in close proximity with the inferior alveolar nerve.
Costantinides, Fulvia, Maglione, Michele, Martin, Andrea, Perinetti, Giuseppe   +3 more
core   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

Pathological Grade-Associated Transcriptome Profiling of lncRNAs and mRNAs in Gliomas

Frontiers in Oncology, 2020
The aim of the present study was to explore the expression profiles of lncRNAs and mRNAs in glioma patients and to elucidate any potential relationship between lncRNAs and mRNAs in glioma.
Junlong Sun, Junlong Sun, Junlong Sun, Rui Jiang, Rui Jiang, Mengruo Song, Mengruo Song, Junzhong Yao, Junzhong Yao, Shiqiang Hou, Yunhua Zhu, Yunhua Zhu, Xiang Ji, Xiang Ji, Hao Sheng, Zhongyu Tang, Zhongyu Tang, Qianqian Liu, Qianqian Liu, Zhongzheng Jia, Wei Shi, Wei Shi, Jinlong Shi, Jinlong Shi   +23 more
doaj   +1 more source

DLX5 regulates the osteogenic differentiation of spinal ligaments cells derived from ossification of the posterior longitudinal ligament patients via NOTCH signaling

JOR Spine, 2023
Background Ossification of the posterior longitudinal ligaments (OPLL) is common disorder characterized by heterotopic ossification of the spinal ligaments. Mechanical stimulation (MS) plays an important role in OPLL.
Tao Tang, Zhengya Zhu, Zhongyuan He, Fuan Wang, Hongkun Chen, Shengkai Liu, Mingbin Zhan, Jianmin Wang, Wei Tian, Dafu Chen, Xinbao Wu, Xizhe Liu, Zhiyu Zhou, Shaoyu Liu   +13 more
doaj   +1 more source

Interleukin-1β overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents

Molecular Pain, 2016
Background Chronic pain is often accompanied by short-term memory deficit and depression. Currently, it is believed that short-term memory deficit and depression are consequences of chronic pain.
Wen-Shan Gui, Xiao Wei, Chun-Lin Mai, Madhuvika Murugan, Long-Jun Wu, Wen-Jun Xin, Lijun Zhou, Xian-Guo Liu   +7 more
semanticscholar   +1 more source