Advancing Chronic Wound Healing through Electrical Stimulation and Adipose‐Derived Stem Cells
Chronic cutaneous wounds represent significant challenges due to delayed healing and resistance to conventional treatments. This review explores the potential of combining adipose‐derived stem cells with electrical stimulation to enhance wound healing.
Qiuyue Peng+5 more
wiley +1 more source
Simultaneous submicrometric 3D imaging of the micro-vascular network and the neuronal system in a mouse spinal cord [PDF]
Defaults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking knowledge of the complete fine structure of VN and neuronal systems is a crucial problem.
arxiv
This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim+8 more
wiley +1 more source
Reduced functional connectivity within the primary motor cortex of patients with brachial plexus injury [PDF]
This study aims at the effects of traumatic brachial plexus lesion with root avulsions (BPA) upon the organization of the primary motor cortex (M1). Nine right-handed patients with a right BPA in whom an intercostal to musculocutaneous (ICN-MC) nerve transfer was performed had post-operative resting state fRMI scanning.
arxiv
Rotator cuff tears, a common musculotendinous injury, often lead to permanent functional disability. A novel hyaluronic acid‐based hydrogel shows promise in promoting muscle regeneration after rotator cuff repair. The hydrogel reduces fibrosis, fatty infiltration, and muscle atrophy while supporting vascularization in a murine model.
Morgan R. Pfaff+11 more
wiley +1 more source
A causal examination of the correlation between hormonal and reproductive factors and low back pain
BackgroundThe relationship between hormonal fluctuations in the reproductive system and the occurrence of low back pain (LBP) has been widely observed. However, the causal impact of specific variables that may be indicative of hormonal and reproductive ...
Dafu Chen+18 more
doaj +1 more source
Engineering the Future of Restorative Clinical Peripheral Nerve Surgery
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell+5 more
wiley +1 more source
UNILATERAL INVOLVEMENT OF THE OPTIC NERVE IN HEAD INJURIES [PDF]
F. C. Rodger
openalex +1 more source
Actuated Hydrogel Platforms To Study Brain Cell Behavior
The complex and dynamic viscoelastic properties of the brain underpin neural plasticity and overall function. Actuating hydrogel platforms support mechanistic research to elucidate how brain cells respond to dynamic microenvironments. This study reviews the mechanobiology of the brain and its impact on brain function in health and disease and describes
Kirill E. Zhurenkov+3 more
wiley +1 more source
Oriented artificial nanofibers and laser induced periodic surface structures as substrates for Schwann cells alignment [PDF]
People with injuries to the peripheral nervous system, due to its poor functional regeneration, suffer from paralysis of the facial muscles, fingers and hands, or toes and feet, often for the rest of their lives. Therefore, to improve patients' quality of life, there is an urgent need for conduits that effectively support the healing of large defects ...
arxiv