Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang +5 more
wiley +1 more source
Pregabalin beyond pain: A neuroprotective alternative in peripheral nerve injury. [PDF]
Alcántara Montero A.
europepmc +1 more source
A Transnasal Endoscope for Robotically Assisted Gastroscopy
This work introduces a 4.25 mm diameter magnetically navigated transnasal endoscope for upper gastrointestinal (GI) screening and intervention. The system enables precise remote steering throughout the upper GI tract and is demonstrated through in vitro and in vivo experiments, including the robotic execution of preprogrammed retroflexions, trans ...
Alexandre Mesot +6 more
wiley +1 more source
Research hotspots and emerging trends of macrophages in peripheral nerve injury: a bibliometric and visualization analysis. [PDF]
Jiang G +7 more
europepmc +1 more source
Shear‐Isolating Actuation System for Exosuit Using Movable Pulley With Webbing‐Driven Mechanism
Tendon‐driven exosuits can chafe the skin because the moving tendon slides against the wearer. A shear‐isolating actuation system combining a movable pulley with flat‐profile webbing keeps the body‐contacting tendon layer stationary, relocating relative motion away from the skin. The compact 145‐g actuator delivers 150 N of assistance, and benchtop and
Kyeongmin Lim +5 more
wiley +1 more source
Detection of Inferior Alveolar Nerve Injury and Prediction of Sensory Recovery. [PDF]
Dong Y +5 more
europepmc +1 more source
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong +14 more
wiley +1 more source
Neuroimmune Interactions in Chronic Pain and Neuroinflammation: Peripheral Nerve Injury, Neuroimmune Mechanisms, and Therapeutic Recovery. [PDF]
Anwar AI +8 more
europepmc +1 more source
A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu +7 more
wiley +1 more source
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source

