Results 31 to 40 of about 204,651 (234)
Neuroprotective efficacy of P7C3 compounds in primate hippocampus. [PDF]
, 2018 There is a critical need for translating basic science discoveries into new therapeutics for patients suffering from difficult to treat neuropsychiatric and neurodegenerative conditions.
Bauman, Melissa D +8 more
core +2 more sources
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
Modulation of Negative Work Output from a Steering Muscle of the Blowfly Calliphora Vicina [PDF]
, 1994 Of the 17 muscles responsible for flight control in flies, only the first basalar muscle (b1) is known to fire an action potential each and every wing beat at a precise phase of the wing-beat period.
Dickinson, Michael H., Tu, Michael S.
core
A Deep Learning Approach to Denoise Optical Coherence Tomography Images of the Optic Nerve Head
, 2018 Purpose: To develop a deep learning approach to de-noise optical coherence tomography (OCT) B-scans of the optic nerve head (ONH). Methods: Volume scans consisting of 97 horizontal B-scans were acquired through the center of the ONH using a commercial ...
Aung, Tin +9 more
core +1 more source
A net for extending the optic nerve at enucleation of the eyeball. [PDF]
British Journal of Ophthalmology, 1989 A long section of optic nerve can be obtained during enucleation, when the eyeball is caught in a net made specifically for this purpose. The net is knitted from surgical thread and is in the shape of a barrel with two openings: one wide, one narrow. Separate thread is wrapped around the edge of the wide opening.
openaire +3 more sources
FEBS Open Bio, EarlyView.The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli +15 more
wiley +1 more source
A new light on nets of C*-algebras and their representations
, 2011 The present paper deals with the question of representability of nets of C*-algebras whose underlying poset, indexing the net, is not upward directed.
Ruzzi, Giuseppe, Vasselli, Ezio
core +1 more source
Extent and mechanism of sealing in transected giant axons of squid and earthworms [PDF]
, 1994 Transected axons are often assumed to seal at their cut ends by the formation of continuous membrane barriers that allow for the restoration of function in the axonal stumps.
Ballinger, Martis L. +3 more
core +1 more source
Nerve net differentiation in medusa development of Podocoryne carnea
Scientia Marina, 2000 The phylum Cnidaria is the most primitive phylum with a well-developed nervous system. Planula larvae and polyps display a diffuse nerve net (plexus), which is densest in the polyp hypostome. In contrast, the nervous system of the medusa is more complexly structured and reflects the anatomical needs of a well differentiated non-sessile animal.
Hans Gröger, Volker Schmid
openaire +4 more sources
FEBS Open Bio, EarlyView.Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal +2 more
wiley +1 more source