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Natural PolymerâDerived Bioscaffolds for Peripheral Nerve Regeneration
Advanced Functional Materials, 2022In recent decades, artificial nerve scaffolds have become a promising substitute for peripheral nerve repair. Considerable efforts have been devoted to improving the therapeutic effectiveness of artificial scaffolds.
Hui Zhang +5 more
semanticscholar +1 more source
Annual Review of Neuroscience, 1990
Schwann cell basal laminae were demonstrated to serve as efficient conduits for the growth of regenerating axons in frozen nerve grafts, and in in situ freezing experiments. Regenerating axonal sprouts usually emanated from the first node of Ranvier proximal to the site of damage, and grew out along the inner surface of the basal lamina.
J W, Fawcett, R J, Keynes
openaire +4 more sources
Schwann cell basal laminae were demonstrated to serve as efficient conduits for the growth of regenerating axons in frozen nerve grafts, and in in situ freezing experiments. Regenerating axonal sprouts usually emanated from the first node of Ranvier proximal to the site of damage, and grew out along the inner surface of the basal lamina.
J W, Fawcett, R J, Keynes
openaire +4 more sources
Advanced Functional Materials, 2021
Peripheral nerve injuries are one of the most common types of traumatic damage to the nervous system. Treatment of peripheral nerve injuries aims to promote axon regrowth by imitating and improving the microenvironment for sciatic nerve regeneration.
Ying Li +9 more
semanticscholar +1 more source
Peripheral nerve injuries are one of the most common types of traumatic damage to the nervous system. Treatment of peripheral nerve injuries aims to promote axon regrowth by imitating and improving the microenvironment for sciatic nerve regeneration.
Ying Li +9 more
semanticscholar +1 more source
Neurosurgery Clinics of North America, 1991
The success of peripheral nerve regeneration is dependent on the survival of axotomized neurons, the efficacy of axonal outgrowth from those neurons, and the specificity of reinnervation of peripheral targets by those neurons. Experimental evidence indicates that following peripheral injury, primary sensory (DRG) neurons and in some cases, motoneurons ...
F J, Liuzzi, B, Tedeschi
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The success of peripheral nerve regeneration is dependent on the survival of axotomized neurons, the efficacy of axonal outgrowth from those neurons, and the specificity of reinnervation of peripheral targets by those neurons. Experimental evidence indicates that following peripheral injury, primary sensory (DRG) neurons and in some cases, motoneurons ...
F J, Liuzzi, B, Tedeschi
openaire +2 more sources
Nerve regeneration and nerve repair
Neurological Research, 2008(2008). Nerve regeneration and nerve repair. Neurological Research: Vol. 30, Nerve Regeneration and Nerve Repair, pp. 997-998.
Rajiv, Midha, Eric L, Zager
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Advances in Materials
Nerve guidance conduits (NGCs) are considered as promising treatment strategy and frontier trend for peripheral nerve regeneration, while their therapeutic outcomes are limited by the lack of controllable drug delivery and available physicochemical cues.
Dongyu Xu +8 more
semanticscholar +1 more source
Nerve guidance conduits (NGCs) are considered as promising treatment strategy and frontier trend for peripheral nerve regeneration, while their therapeutic outcomes are limited by the lack of controllable drug delivery and available physicochemical cues.
Dongyu Xu +8 more
semanticscholar +1 more source
Current Opinion in Neurology, 1995
The regeneration of nerve is a brilliant example of plasticity within the nervous system. Axonal sprouts form within a few hours of nerve injury and grow vigorously over long distances. Nonetheless, recovery from nerve injury, such as that seen after laceration of distal motor-sensory nerve, is often incomplete.
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The regeneration of nerve is a brilliant example of plasticity within the nervous system. Axonal sprouts form within a few hours of nerve injury and grow vigorously over long distances. Nonetheless, recovery from nerve injury, such as that seen after laceration of distal motor-sensory nerve, is often incomplete.
openaire +2 more sources
2005
The nerve chamber model has dominated the experimental study of peripheral nerve (PN) regeneration with animal models as well as in several clinical applications, such as the treatment of paralysis of limbs following severe trauma. The two stumps resulting from nerve transection are inserted inside a tubular chamber made from one of several materials ...
Mei, Zhang, Ioannis V, Yannas
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The nerve chamber model has dominated the experimental study of peripheral nerve (PN) regeneration with animal models as well as in several clinical applications, such as the treatment of paralysis of limbs following severe trauma. The two stumps resulting from nerve transection are inserted inside a tubular chamber made from one of several materials ...
Mei, Zhang, Ioannis V, Yannas
openaire +2 more sources
Electrically Conductive Hydrogel Nerve Guidance Conduits for Peripheral Nerve Regeneration
Advanced Functional Materials, 2020Peripheral nerve injuries are serious conditions, and surgical treatment has critical limitations. Therefore, nerve guidance conduits (NGCs) are proposed as an alternative.
Junggeon Park +9 more
semanticscholar +1 more source
Neuroscience Research, 1996
Peripheral nerve regeneration comprises the formation of axonal sprouts, their outgrowth as regenerating axons and the reinnervation of original targets. This review focuses on the morphological features of axonal sprouts at the node of Ranvier and their subsequent outgrowth guided by Schwann cells or by Schwann cell basal laminae.
openaire +2 more sources
Peripheral nerve regeneration comprises the formation of axonal sprouts, their outgrowth as regenerating axons and the reinnervation of original targets. This review focuses on the morphological features of axonal sprouts at the node of Ranvier and their subsequent outgrowth guided by Schwann cells or by Schwann cell basal laminae.
openaire +2 more sources