Results 71 to 80 of about 420,565 (296)

Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF [PDF]

open access: yes, 2002
Injury to peripheral nerves results in the infiltration of immune cells, which remove axonal- and myelin-derived material. Schwann cells could play a key role in this process by regulating macrophage infiltration.
George K. Tofaris   +7 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Pharmacotherapy in Mental Disorders: Critical Reconsideration

open access: yesОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева, 2018
In this paper, traditional concepts of on link between mental activity and brain activity are reviewed, and hypothesis of brain as a biological interface, which was earlier (2008) suggested by the author, is developed. Approaches to research of psyche in
M. M. Reshetnikov
doaj  

Macroanatomical study on origin and distribution of Caucasian Lynx (Lynx lynx dinniki)’s the brachial plexus

open access: yesRevista Científica
This study aimed to determine the formation of the plexus brachialis, the nerves that ramify from the plexus, and their last branches in the Caucasian Lynx.
Lutfi Takcı, Hasan Hüseyin Arı
doaj   +1 more source

Nerves originating from brachial plexus in the porcupine (Hystrix cristata)

open access: yesVeterinární Medicína, 2004
In this study, dissemination of forelimb's nerves of the porcupine (Hystrix cristata) was investigated. Four porcupines (two males and two females) were used and nerves originating from brachial their plexus were dissected.
A. Aydin
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Sonoanatomic fundamentals of musculoskeletal ultrasound

open access: yesIndian Journal of Rheumatology, 2018
Over the years, anatomists have discerned basic anatomic principles that are applicable to the understanding of the structure and function of the superficial “soft tissues” of the human body including fascia, tendon, muscle, enthesis and nerve ...
Ingrid Moller   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

FORMATION OF SPINAL NERVES. POSTERIOR BRANCHES OF SPINAL NERVES.

open access: yes
Each nerve forms from nerve fibers, known as fila radicularia, extending from the posterior (dorsal) and anterior (ventral) roots of the spinal cord. The roots connect via interneurons.
Khalilov, Sanjar   +7 more
core   +1 more source

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