Results 101 to 110 of about 2,389,964 (125)
The Role of IRE1 Signaling in the Central Nervous System Diseases
The accumulation of misfolded or unfolded proteins in endoplasmic reticulum (ER) lumen results in the activation of an adaptive stress process called the unfolded protein response (UPR).
H. Ni+4 more
semanticscholar +1 more source
Backgrounds of Speech Disorders in Children with Down Syndrome. An Early Logopedic Intervention
Speech development of children with a Down syndrome is partly stunted or disturbed in comparison to healthy children’s speech, although, it is subjected to the same rules.
Teresa Kaczan+2 more
doaj +1 more source
Achieving Control of Lesion Growth in CNS with Minimal Damage [PDF]
Lesions in central nervous system (CNS) and their growth leads to debilitating diseases like Multiple Sclerosis (MS), Alzheimer's etc. We developed a model earlier which shows how the lesion growth can be arrested through a beneficial auto-immune mechanism.
arxiv
Antibody-mediated central nervous system diseases
Antibody-mediated central nervous system diseases are a relatively new area of clinical neuroscience with growing impact. Their recognition has challenged the dogma of the blood–brain barrier preventing antibody access into the central nervous system ...
M. P. Giannoccaro, S. Crisp, A. Vincent
semanticscholar +1 more source
Introduction. Noonan syndrome (NS) is a genetically determined disease, inherited from autosomal dominant. About 50% of patients have a mutation in the PTPN11 gene, and mutations in the other genes are much less frequent, up to 10–15% for SOS1, RAF1, and
Teresa Kaczan+4 more
doaj +1 more source
A Mathematical Model for Skin Sympathetic Nerve Activity Simulation [PDF]
Autonomic nervous system is important for cardiac function regulation. Modeling of autonomic cardiac regulation can contribute to health tracking and disease management. This study proposed a mathematical model that simulates autonomic cardiac regulation response to Valsalva Maneuver, which is a commonly used test that provokes the autonomic nervous ...
arxiv
The Gut Microbiome as Therapeutic Target in Central Nervous System Diseases: Implications for Stroke
Research on commensal microbiota and its contribution to health and disease is a new and very dynamically developing field of biology and medicine.
Katarzyna Winek, U. Dirnagl, A. Meisel
semanticscholar +1 more source
A Sympathetic Nervous System Theory of Migraine [PDF]
Migraine (MGR) ranks first among diseases in terms of years of lost healthy life in young adult and adult women. Currently, there is no theory of MGR. This paper presents a complete theory of migraine that explains its etiology, symptoms, pathology, and treatment.
arxiv
Interplay between androgen and CXCR4 chemokine signaling in myelin repair
In men, reduced levels of testosterone are associated with the prevalence and progression of multiple sclerosis (MS), a chronic and disabling demyelinating disorder. Testosterone has been shown to promote myelin repair.
Narimène Asbelaoui+7 more
doaj +1 more source
A temporal model for multiple sclerosis course evolution [PDF]
Multiple Sclerosis is a degenerative condition of the central nervous system that affects nearly 2.5 million of individuals in terms of their physical, cognitive, psychological and social capabilities. Researchers are currently investigating on the use of patient reported outcome measures for the assessment of impact and evolution of the disease on the
arxiv