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Genetic Diseases of the Nervous System
2009All human diseases, including those of the nervous system, are the result of interactions between genetic factors and the environment. In some diseases the genetic factors are relatively minor and of little importance. Other disorders are strictly inherited conditions, and genetic factors are paramount.
Thomas D. Bird, Suman Jayadev
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MAN'S NERVOUS SYSTEM AND DISEASE
Archives of Neurology, 1961The population of the United States has increased approximately 50% in the last 30 years. During this same period, life expectancy at birth has increased from 60 to 70 years. In terms of the total number of deaths from all causes, it is estimated that the number of those who died from lesions within the nervous system has changed but little in these 30
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Paraneoplastic diseases of the nervous system
Current Treatment Options in Neurology, 1999Several neurologic paraneoplastic disorders are believed to be caused by an autoimmune reaction against an antigen or antigens coexpressed by tumor cells and neurons. Of the paraneoplastic syndromes, the Lambert-Eaton myasthenic syndrome (LEMS)--in which autoantibodies downregulate voltage-gated calcium channels at the presynaptic nerve terminal--is ...
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Metastatic disease of the nervous system
Current Treatment Options in Neurology, 1999Nervous system metastases occur in about 25% of patients with systemic cancer (Table 1) and usually involve the brain parenchyma, leptomeninges, and spinal epidural space. Although they are ominous, they can be effectively treated in many patients, reducing disability and prolonging life.
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Behçet's disease and the nervous system
Journal of Neurology, 1998Behçet's disease is a multisystem inflammatory disorder with unknown aetiology. It is a disease of young adults with a more severe course in males subjects. Its prevalence is high in the Mediterranean basin and Japan and has been linked with human leucocyte antigen B5 (HLA-B5) in those countries.
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Thyroid disease and the nervous system
2014Thyroid disorders are common in the general population and in hospitalized patients. Thyroid disease may present first with neurological complications or else may occur concurrently in patients suffering other neurological disorders, particularly those with an autoimmune etiology.
Clare A, Wood-Allum, Pamela J, Shaw
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Spirochetal diseases of the nervous system
Current Opinion in Neurology, 1994Neurosyphilis and neuroborreliosis are currently the most important spirochetal diseases that can affect the human nervous system. This review presents current concepts of the epidemiology, clinical manifestations, laboratory diagnosis, and management of these disorders, and it provides special emphasis on the management of patients with both HIV ...
R, Cintron, A R, Pachner
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VIRUS DISEASES OF THE NERVOUS SYSTEM
Journal of the American Medical Association, 1946The clinical pictures of virus diseases of the nervous system do not depend on peculiarities of the viruses which cause them but on the location of the lesions produced. Irritative and destructive agents, regardless of their characteristics, produce similar clinical pictures if and when they attack the same parts of the brain and cord.
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Infectious Diseases of the Nervous System
Seminars in Pediatric Neurology, 2011The curriculum for child neurology trainees should include information regarding the many infectious and post-infectious disorders that affect the developing nervous system. This article provides recommendations regarding the nature of the educational content and suggestions how this content can be provided to trainees.
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Retroviruses and nervous system disease
Current Opinion in Neurobiology, 1992During the past decade retroviruses have been recognized as causes of human neurological disease. A wide clinical spectrum of neurological and neuromuscular diseases have been reported with HIV infections, and studies of these diseases have raised novel and exciting hypotheses of pathogenesis.
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