Results 271 to 280 of about 2,663,952 (341)

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Oxazole-Based Ferroptosis Inhibitors with Promising Properties to Treat Central Nervous System Diseases. [PDF]

J Med Chem
Scarpellini C, Klejborowska G, Lanthier C, Toye A, Musiałek K, Van San E, Walravens M, Berg M, Hassannia B, Van der Veken P, De Winter H, Vanden Berghe T, Augustyns K.   +12 more
europepmc   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

Advanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz, Noa Ben David, Adi Gross, Boaz Mizrahi   +3 more
wiley   +1 more source

Exosomes in Central Nervous System Diseases: A Comprehensive Review of Emerging Research and Clinical Frontiers. [PDF]

Biomolecules
Li J, Song J, Jia L, Wang M, Ji X, Meng R, Zhou D.   +6 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

HLA-transgenic mouse models to study autoimmune central nervous system diseases. [PDF]

Autoimmunity
Pressley KR, Schwegman L, Montes De Oca Arena M, Chase Huizar C, Zamvil SS, Forsthuber TG.   +5 more
europepmc   +1 more source

Neuropsychiatric symptoms correlated with autoimmune diseases of the nervous system

Przemysław Robert Dalski-Szeląg, Roksana Grzeszczak, Milena Zaremba, Magdalena Grabińska, Wojciech Mikołaj Szkudlarek, Maksym K. Gmur   +5 more
openalex   +2 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Neurosurgical gene therapy for central nervous system diseases. [PDF]

Neurotherapeutics
Patel RV, Nanda P, Richardson RM.
europepmc   +1 more source