Results 61 to 70 of about 2,814,068 (394)

RETRACTED ARTICLE: GRP78 determines glioblastoma sensitivity to UBA1 inhibition-induced UPR signaling and cell death

open access: yesCell Death and Disease, 2021
Glioblastoma multiforme (GBM) is an extremely aggressive brain tumor for which new therapeutic approaches are urgently required. Unfolded protein response (UPR) plays an important role in the progression of GBM and is a promising target for developing ...
Guanzheng Liu   +13 more
doaj   +1 more source

Hereditary neuropathy with liability to pressure palsies: a case report

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
Hereditary neuropathy with liability to pressure palsies (HNPP) is a rare hereditary disorder characterized by recurrent episodes of nerve compression. The first attack usually occurs in the second or third decade of life.
A. K. Polynnikova   +3 more
doaj   +1 more source

Cognitive impairments in patients with prior ischemic stroke

open access: yesНеврология, нейропсихиатрия, психосоматика, 2014
The authors give the data available in the literature on and the results of their studies of the epidemiology, risk factors, pathogenesis, diagnosis, and treatment of poststroke cognitive impairment (PSCI).
V. A. Parfenov   +4 more
doaj   +1 more source

UBA1 inhibition contributes radiosensitization of glioblastoma cells via blocking DNA damage repair

open access: yesFrontiers in Pharmacology, 2023
Glioblastoma multiforme (GBM) is a brain tumor with high mortality and recurrence rate. Radiotherapy and chemotherapy after surgery are the main treatment options available for GBM. However, patients with glioblastoma have a grave prognosis.
Changyong Wu   +16 more
doaj   +1 more source

The Occupational Safety and Health Act of 1970 and the Law of Torts [PDF]

open access: yes, 1974
INTRODUCTION: A patients needs and the seriousness of the disease are not the only factors that determine referral to hospital. The objective of this study was to analyse whether locum doctors (LDs) have a different pattern of referral to hospital from ...
Faresjö, Tomas, Gjessing, Kristian
core   +3 more sources

SWAP-70 promotes glioblastoma cellular migration and invasion by regulating the expression of CD44s

open access: yesCancer Cell International, 2019
Background Switch-associated protein 70 (SWAP-70) is a guanine nucleotide exchange factor that is involved in cytoskeletal rearrangement and regulation of migration and invasion of malignant tumors.
Lin Shi   +12 more
doaj   +1 more source

Neurodegeneration: From cellular concepts to clinical applications [PDF]

open access: yes, 2016
Developing therapies for neurodegenerative diseases will require new scientific approaches that take into account the detrimental effects of altered protein and RNA homeostasis on brain cells, the vulnerabilities of various organelles in certain diseases
De Strooper, B   +2 more
core   +1 more source

Central pontine myelinolysis in the presence of SARS-CoV-2 infection (clinical observations)

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
Osmotic demyelinating syndrome (ODS) is a severe complication that occurs due to rapid correction of hyponatremia. Central  pontine myelinolysis (CPM), in which a focus of demyelination  occurs in the pontine region, and extrapontine myelinolysis (EPM), 
O. N. Voskresenskaya   +5 more
doaj   +1 more source

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