Advantages of CRISPR-Cas9 combined organoid model in the study of congenital nervous system malformations [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 In the past 10 years, gene-editing and organoid culture have completely changed the process of biology. Congenital nervous system malformations are difficult to study due to their polygenic pathogenicity, the complexity of cellular and neural regions of ...
Li Xiaoshuai, Wang Qiushi, Wang Rui
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Complex central nervous system malformations in a Dutch Warmblood foal [PDF]
Journal of Veterinary Internal Medicine, 2022 A neonatal Dutch Warmblood colt was evaluated for inability to stand, incoordination and intention tremor. Despite partial improvement in clinical signs during the first 4 days of hospitalization, neurological deficits remained.
Elizabeth Williams Louie +5 more
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Nervous System Malformations. [PDF]
Continuum (Minneap Minn), 2018 This article provides an overview of the most common nervous system malformations and serves as a reference for the latest advances in diagnosis and treatment.Major advances have occurred in recognizing the genetic basis of nervous system malformations.
Gaitanis J, Tarui T.
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Central nervous system vascular malformations: A clinical review [PDF]
Annals of Clinical and Translational Neurology, 2021 CNS vascular malformation is an umbrella term that encompasses a wide variety of pathologies, with a wide range of therapeutic and diagnostic importance.
Behnam Sabayan +4 more
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Identifying Immune Cells as Mediators in the Impact of Gut Microbiota on Congenital Malformations of the Nervous System [PDF]
Brain and BehaviorIntroduction Congenital malformations of the nervous system, such as neural tube defects, are significant contributors to infant morbidity and mortality.
Haokun Tian +12 more
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Study of Central Nervous System Malformations of Perinatal Autopsies [PDF]
Perspectives In Medical Research, 2023 Background: Congenital malformations remain a common cause of perinatal deaths accounting for 10-15% in developing countries like India. They are the most severe disorders of the central nervous system.
Anuradha G Patil +3 more
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A long-term follow-up study of adults with Chiari malformation type I combined with syringomyelia
Frontiers in Neurology, 2023 BackgroundThere is a considerable amount of controversy regarding the treatment and prognosis of adult patients with Chiari malformation type I (CM-I) at home and abroad; furthermore, no large-sample, long-term, follow-up studies have examined CM-I ...
Yan Hu +11 more
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Atlas of Nervous System Vascular Malformations: A Systematic Review
Life, 2022 Vascular malformations are frequent in the head and neck region, affecting the nervous system. The wide range of therapeutic approaches demand the correct anatomical, morphological, and functional characterization of these lesions supported by imaging ...
Carlos Castillo-Rangel +15 more
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Evaluation of Fetal Central Nervous System Anomalies by Ultrasound and Its Anatomical Co-relation [PDF]
Journal of Clinical and Diagnostic Research, 2014 Introduction: Central nervous system anomalies are often severe and are the most common indications for therapeutic abortions. Ultrasound examination helps to identify and evaluate them well before birth.
DEEPALI ONKAR +2 more
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RMD Open, 2023 Objectives The aim of this study was to determine the risk of congenital malformations in offspring born to women with systemic lupus erythematosus (SLE).Methods This nationwide population-based study included Korean women who had a singleton pregnancy ...
Jin Kyun Park +7 more
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