Results 121 to 130 of about 124,681 (307)

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

Cinematic innervation: the intuitive form of perception in the distracted perceptual field

Journal of Aesthetics & Culture, 2013
In “The Work of Art in the Age of Its Technological Reproducibility,” Walter Benjamin alluded that the human perceptual field in his time would become more distracted by the intervention of technologies, and so masses’ tactility ...
Sungyong Ahn
doaj   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

From Mary Shelley to Netflix: a Pan-European perspective on public communication of neuroscience and neurotechnology

Frontiers in Neuroscience
Scientific knowledge of the human brain has captivated the public’s attention and sparked their imagination for centuries. Comprehending the inner workings of the mind and the underlying molecular and physiological aspects of the central nervous system ...
Ángeles Consuelo Gallar Martínez, Alicia De Lara González   +1 more
doaj   +1 more source

Treatment of climacteric disorders in menopause [PDF]

РМЖ. Мать и дитя, 2018
Treatment of climacteric disorders in menopause Radzinsky V.E., Ordiyants I.M. Peoples’ Friendship University of Russia, Moscow The onset of menopause is one of the most critical periods in a woman’s life.
V.E. Radzinskiy, I.M. Ordiyants
doaj  

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Elimination of Functional Synapses During Development of the Nervous System

, 1987
Prevailing views of how axonal projections and synapses are formed during development have changed during the last 2 decades. In many structures abundant collaterals and redundant synapses are first formed, then supernumerary axonal branches are ...
J Mariani, N Delhaye-Bochaud
core   +1 more source

Towards a neurophysiological model of kundalini: a theoretical framework informed by preliminary clinical observations

Frontiers in Behavioral Neuroscience
The purpose of the present paper is not to validate the metaphysical claims of yogic traditions, but to examine whether their phenomenological descriptions correspond to measurable physiological processes.
Swapan Samanta, Nirmal Sultania, Mukul Roychoudhury, Surendra Sharma, Paritosh Mitra   +4 more
doaj   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Neurophysiological and histopathological evaluation of small fiber pathways as diagnostic characterization of neuropathic pain and autonom dysfunction syndromes

, 2012
This manuscript is made up of two individual not related articles about peripheral neuropathic pain syndrome. The first article reports the effect on pain relief in patients with peripheral neuropathic pain after brachial plexus lesions or distal ...
Devigli, Grazia, Devigili, Grazia
core