Results 81 to 90 of about 124,681 (307)

Microengineered Gradient Hydrogels for Mechanobiology

open access: yesAdvanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong   +4 more
wiley   +1 more source

"In silico" prediction of drug transport across physiological barriers [PDF]

open access: yes, 2011
Physiological barriers maintain and safeguard homeostasis of certain body compartments by an increased resistance against free diffusion. Distribution and pharmacokinetics of drugs can be altered as well, if they have to cross these barriers in order to ...
Suenderhauf, Claudia
core   +1 more source

Optimization of Movement: A Dynamical Systems Approach to Movement Systems as Emergent Phenomena.

open access: yesPhysical Therapy, 2018
The term "movement system" has been defined as "represent(ing) the collection of systems (cardiovascular, pulmonary, endocrine, integumentary, nervous, and musculoskeletal) that interact to move the body or its component parts."5 Although we do not ...
A. Guccione, Brian T. Neville, S. George
semanticscholar   +1 more source

A Data Driven Review of In Vitro Electrical and Mechanical Stimulation for Post‐Acute Phase Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess   +3 more
wiley   +1 more source

A systemic analysis of the ideas immanent in neuromodulation

open access: yes, 2008
This thesis focuses on the phenomena of neuromodulation — these are a set of diffuse chemical pathways that modify the properties of neurons and act in concert with the more traditional pathways mediated by synapses (neurotransmission).
Buckley, Christopher Laurie
core  

Embracing cancer complexity: Hallmarks of systemic disease

open access: yesCell
SUMMARY The last 50 years have witnessed extraordinary developments in understanding mechanisms of carcinogenesis, synthesized as the hallmarks of cancer. Despite this logical framework, our understanding of the molecular basis of systemic manifestations
C. Swanton   +32 more
semanticscholar   +1 more source

Simultaneous Electrochemical Detection of NGF and proNGF Under Native Conditions Using Molecularly Imprinted Polymers: Toward Point‐of‐Care Diagnosis of Alzheimer's Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
This study relies on the development of a new sensor that can detect two closely related proteins involved in Alzheimer's disease at the same time. Unlike traditional methods, it works in natural conditions and does not require sample pretreatment. The device is highly sensitive and was successfully tested on patient samples, offering promises for ...
Giulia Siciliano   +12 more
wiley   +1 more source

Physiological effects of heart rate variability biofeedback during laboratory induced congnitive stress

open access: yes, 2012
Includes bibliographical references.Heart rate variability (HRV) biofeedback is effective in reducing stress as well as managing chronic disease. It facilitates easy manipulation of HRV, and, therefore, potentially provides a valuable intervention for ...
Prinsloo, Gabriell Elizabeth
core  

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină   +2 more
wiley   +1 more source

Thermal signatures of human pheromones in sexual and reproductive behaviour

open access: yes, 2010
Chemically mediated sexual communication in humans has been largely neglected due to its non-conscious and relatively concealed nature. However, menstrual cycle synchronisation, puberty onset in young pre-pubertal girls exposed to their stepfather, and ...
Andrea Mazzatenta   +3 more
core  

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