Results 121 to 130 of about 107,393 (252)
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu +7 more
wiley +1 more source
Integrative Cross-platform Analysis of Kinase Inhibitor Effects on Statin-relevant Cardioprotective Pathways in Human Cardiomyocytes. [PDF]
Kuo TY +4 more
europepmc +1 more source
Enantioselective Access to Trifluoromethylated Spirocyclopropyl Heterocycles
We report a rhodium‐catalyzed asymmetric [2+1] spirocyclopropanation of methylene azacycles with trifluoromethyl carbenes in situ derived from fluoroalkyl triftosylhydrazones. ABSTRACT Chiral spirocyclopropyl heterocycles have emerged as privileged three‐dimensional structural motifs in medicinal chemistry.
Yuanhao Zhu +9 more
wiley +1 more source
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li +6 more
wiley +1 more source
Association of English language proficiency and breast cancer oncologic outcomes. [PDF]
Ravella R +9 more
europepmc +1 more source
Constrained Forest Methane Sink by Thermal Adaptation of Soil Methanotrophs
Climate warming can stimulate methanotroph‐mediated CH4 oxidation in forest soils, thereby mitigating the increase in atmospheric CH4 concentrations. By integrating evidence from a macro‐climatic thermal gradient and a 70‐day incubation experiment, this study demonstrates that microbial methanotrophs can adapt to long‐term temperature changes at the ...
Baizhi Jiang +5 more
wiley +1 more source
Association of Night Eating Syndrome Risk with Sleep Disturbance in Medical Students: A Cross-Sectional Study. [PDF]
Tekin V +5 more
europepmc +1 more source
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu +23 more
wiley +1 more source
Distribución de la caries dental en niños preescolares en una región urbana, Argentina, 1992
Se describen los resultados de una investigación desarollada sobre una muestra de 1.115 preescolares (5 años) de jardines de infantes de la Ciudad de Córdoba (Argentina), destinada a establecer la prevalencia y distribución de la caries dental conforme a
Elba Rosa Luna Maldonado de Yankilevich +3 more
doaj

