Results 181 to 190 of about 1,308,166 (292)

A Wood Plasticine With Controlled Phase‐Change Behavior and Malleability for Energy‐Closed‐Loop and Conformally Adaptive Thermal Management

Advanced Science, EarlyView.
A photothermal wood plasticine exhibiting controlled phase‐change behavior and malleable property is developed. The developed wood plasticine can provide all‐day, on‐demand, and low‐loss solar heating for geometrically diverse objects, including thermoelectric generator, human body, and battery, through its controlled crystallization‐melting ...
Jiazuo Zhou, Yifan Liu, Lei Qiao, Yuehe Gu, Taikun Yao, Wenbo Zhang, Fangmiao Wang, Yudong Li, Xinyao Ji, Lingyi Kong, Haiyue Yang, Yao Xiao, Chengyu Wang   +12 more
wiley   +1 more source

Cas10 residues lining the target RNA binding channel regulate interference by distinguishing cognate target RNA from mismatched targets. [PDF]

RNA Biol
Khweis SA, Blackburn MA, Perdigao CC, Pierce MO, Lewis CR, Dunkle JA.   +5 more
europepmc   +1 more source

Directed Evolution Improves the Catalytic Efficiency of APEX2‐Mediated Proximity‐Dependent RNA Labeling

Advanced Science, EarlyView.
ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley   +1 more source

A Novel CsYABBY3‐CsAS1 Feedback Loop Coordinates Trichome Differentiation and Cannabinoid Biosynthesis in Cannabis sativa L.

Advanced Science, EarlyView.
A novel transcriptional module involving CsYABBY3 and CsAS1 is identified to regulate cannabinoid biosynthesis and trichome development. These factors mutually activate each other and form a protein complex via a conserved residue, acting synergistically to amplify metabolic flux through a coordinate feed‐forward mechanism.
Xuewen Zhu, Yaolei Mi, Xue Cao, Weiqiang Chen, Pucheng Fan, Jing Wang, Yiming Zhang, Wei Yang, Huihua Wan, Shanshan Chen, Xiangxiao Meng, Jun Li, Shuo Shen, Mingkun Huang, Xiaoyu Zhang, Ming Luo, Shilin Chen, Zhichao Xu, Wei Sun   +18 more
wiley   +1 more source

Examining the gene network and prognostic biomarkers in the onset of colorectal cancer in stool samples using machine learning. [PDF]

Discov Oncol
Shahr RS, Mahmoudi MS, Amirnia N, Karimpour F, Noori A, Khanmirzaei A, Hassania T, Karimikhoshnoudian B, Nasiri P, Javanmard AR.   +9 more
europepmc   +1 more source

Soft and Adhesive Cardiac Patch for Electrophysiological and Contraction Measurement

Advanced Science, EarlyView.
This study developed an epicardial electronic patch with a modulus similar to that of the heart (approximately 65kPa), which can collect stable electrocardiogram signals and myocardial contractility on the surface of a dynamically beating heart. This is attributed to the hydrogen bond interaction formed between the amino and catechol groups in the ...
Wuliang Chen, Xinyu Shen, Hanning Liu, Lamei Du, Caicai Jiao, Longfei Li, Qian Wang, Qiuting Zhang, Lixue Tang, Liang Hu, Yubo Fan   +10 more
wiley   +1 more source

Tandem Duplications in UBTF Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency. [PDF]

Blood Cancer Discov
Barajas JM, Phillips AH, Wang J, Thomas ME, Contreras L, Umeda M, Hiltenbrand R, Caldwell E, Walsh MP, Song G, Ezzell L, Churion K, Westover T, Xiong E, Rolle C, Moore J, Lott J, Radko-Juettner S, Kumar A, Qi W, Xu B, Papachristou EK, D'Santos CS, Ma J, Freeman BB, Janke LJ, Kriwacki RW, Klco JM.   +27 more
europepmc   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

Oral Islatravir in Macaques Decreases Lymphocytes and Monocytes and Is Associated with Immune Alterations. [PDF]

Pharmaceutics
Daly MB, Kim D, Inusah S, Little D, Kim JS, Makarova N, Edwards TE, Mitchell J, Heneine W, Pan Y, Dobard CW, García-Lerma JG.   +11 more
europepmc   +1 more source

Autonomous and Continuous Atmospheric Water Harvesting Using Modified Wood

Advanced Science, EarlyView.
A rigid, hydroxyl‐rich wood skeleton with graded channels is used as a multifunctional host to co‐incorporate a PNipam/PAA network and LiCl, creating a high‐performance sorbent for atmospheric water harvesting. The composite achieves rapid sorption, efficient low‐temperature desorption, and stable cycling, enabling a solar‐powered device with a high ...
Shiheng He, Jiaqi Su, Tianting Leng, Yujian Song, Jidong Dong, Pengfei Huo, Zhenhua Gao, Shuaiyuan Han   +7 more
wiley   +1 more source