Results 41 to 50 of about 107,393 (252)
Revista de Saúde Pública, 1993 Se describen los resultados de una investigación desarollada sobre una muestra de 1.115 preescolares (5 años) de jardines de infantes de la Ciudad de Córdoba (Argentina), destinada a establecer la prevalencia y distribución de la caries dental conforme a
Elba Rosa Luna Maldonado de Yankilevich +3 more
doaj +1 more source
NES-järjestelmän hyödyntäminen pienjänniteverkossa [PDF]
, 2021 Opinnäytetyö on toteutettu Caruna Oy:lle. Tavoitteena oli tutkia Networked Energy Servicen (NES) tarjoamien järjestelmien hyödyntämistä pienjännitejakeluverkon hallinnassa.
Saarinen, Jani
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Passive Suppression of Panel Flutter Using a Nonlinear Energy Sink
International Journal of Aerospace Engineering, 2020 A nonlinear energy sink (NES) is used to suppress panel flutter. A nonlinear aeroelastic model for a two-dimensional flat panel with an NES in supersonic flow is established using the Galerkin method.
Jian Zhou, Minglong Xu, Wei Xia
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Advances in Redox ResearchExcess labile copper catalyzes Fenton-type redox cycling, amplifying reactive oxygen species (ROS) and disrupting mitochondrial and calcium homeostasis. In Wilson’s disease (WD), ATP7B deficiency leads to hepatic copper accumulation and progressive redox-
Itzchak Angel +5 more
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IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
In opdracht van de gemeente Breda heeft het Team Erfgoed van de gemeente Breda meerdere rioleringswerkzaamheden langs de Vlaszak, het Kloosterplein, de Chassé Promenade en de Oude Vest begeleid dan wel als waarneming gedocumenteerd.
Nes, E de
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