Non-insulinoma pancreatogenous hypoglycemia syndrome (NIPHS)/Nesidioblastosis as the underlying cause of recurrent hypoglycemia in a diabetic adult [PDF]
Non-insulinoma pancreatogenous hypoglycemia syndrome (NIPHS), without previous bariatric surgery, is a rare form of hypoglycemia in adult patients and is associated with nesidioblastosis.
Samikshya Thapa +4 more
doaj +3 more sources
This rare case vignette describes hypoglycemic, hyperinsulinemic nesidioblastosis in a female patient with prior Roux-en-Y gastric bypass. The patient presented with severe symptomatic hypoglycemia resistant to IV dextrose and diazoxide, requiring ...
Jessica Cao +6 more
doaj +3 more sources
Adult Nesidioblastosis in Chronic Kidney Disease
Context. Nesidioblastosis is a rare cause of hyperinsulinemic hypoglycemia in adults. The diagnosis is further complicated in patients with kidney failure, since impaired renal function can cause hypoglycemia by itself and diagnostic criteria for this ...
Eduardo Lozano-Melendez +5 more
doaj +3 more sources
Case report: Duplication of the GCK gene is a novel cause of nesidioblastosis: evidence from a case with Silver-Russell syndrome-like phenotype related to chromosome 7 [PDF]
Silver-Russell syndrome (SRS) is a syndrome characterized by prenatal and postnatal growth retardation, facial features, and body asymmetry. SRS is often complicated with hypoglycemia, whose etiology is unclear. We describe the clinical course of 25-year-
Takashi Shoji +19 more
doaj +2 more sources
Clinically Adult-Onset Nesidioblastosis with Repeated Severe Hypoglycemia, Successfully Treated by Two Times Pancreatectomies. A Rare Case Report [PDF]
Wataru Izumo,1 Ryota Higuchi,1 Masahiro Shiihara,1 Shuichiro Uemura,1 Takehisa Yazawa,2 Noriyoshi Takano,3 Atsuhiro Ichihara,3 Toru Furukawa,4 Yoji Nagashima,5 Masakazu Yamamoto,2 Goro Honda1 1Department of Surgery, Institute of Gastroenterology, Tokyo ...
Izumo W +10 more
doaj +2 more sources
Hyperinsulinaemic, hypoglycaemic syndrome due to acquired nesidioblastosis in a cat [PDF]
Case summary A 6-year-old, neutered female British Shorthair cat presented with acute-onset weakness and mental dullness. Initially the cat was mildly hyperglycaemic (9.9 mmol/l; reference interval [RI] 3.3–6.7 mmol/l).
Lydia E Hambrook +3 more
doaj +3 more sources
A hypoglycaemic ‘Peter Pan’: a paediatric disease in an adult patient? [PDF]
A 56-year-old male presented to hospital with vomiting and was admitted for management of suspected aspiration pneumonia. His medical history was significant for a diagnosis of cerebral palsy and intellectual disability and he had suffered regular ...
Shannon McCarthy, Mark Kotowicz
doaj +2 more sources
Nesidioblastosis del adulto. Informe de un caso [PDF]
La nesidioblastosis del adulto es rara. Se define como cambios en el páncreas endocrino caracterizado por la proliferación anormal de las células de los islotes pancreáticos, que afecta en forma difusa a la glándula, y que causa hipoglucemia ...
Liesel Pérez Ruiz +2 more
doaj +1 more source
Diffuse, Adult-Onset Nesidioblastosis/Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome (NIPHS): Review of the Literature of a Rare Cause of Hyperinsulinemic Hypoglycemia [PDF]
Differential diagnosis of hypoglycemia in the non-diabetic adult patient is complex and comprises various diseases, including endogenous hyperinsulinism caused by functional β-cell disorders.
Martin Philipp Dieterle +13 more
doaj +2 more sources
Nesidioblastosis with delayed diagnosis and post-operative complications in a patient with complex psychiatric history [PDF]
Nesidioblastosis is a rare condition of organic persistent hyperinsulinaemic hypoglycaemia, with fewer than 100 cases since it was first recorded. However, an increasing prevalence suggests previous underdiagnosis due to poor knowledge and awareness ...
Lee Ann Santore +3 more
doaj +2 more sources

