Results 31 to 40 of about 166,869 (260)
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Effect of Feathers as Nest Insulation on Incubation Behavior and Reproductive Performance of Tree Swallows (\u3cem\u3eTachycineta bicolor\u3c/em\u3e) [PDF]
Many species of birds line their nests with feathers, presumably because of the insulative qualities of feathers and because feathers may act as a barrier between nest parasites and nestlings.
Faro, Christine A +4 more
core
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Quantum bipolar thermoelectricity
Thermoelectricity is generally understood as a classical effect emerging from energy-dependent transport asymmetries. Here, we uncover a purely quantum mechanism, where a superconducting S-I-S’ tunnel junction in thermal equilibrium develops a nonlinear ...
Filippo Antola +3 more
doaj +1 more source
Ultrafast hot carrier transfer in WS2/graphene large area heterostructures
Charge transfer processes in two-dimensional van der Waals heterostructures enable upconversion of low energy photons and efficient charge carriers extraction.
Chiara Trovatello +8 more
doaj +1 more source
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
Birds build camouflaged nests [PDF]
This work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) (BB/I019502/1 to S.D.H. and S.L.M.) and by Roslin Institute Strategic Grant funding from the BBSRC (to S.L.M).It is assumed that many birds attempt to conceal ...
Meddle, Simone L. +4 more
core +1 more source
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng +4 more
wiley +1 more source
The power of a critical heat engine
The second law of thermodynamics says that the efficiency of a heat engine is limited by the Carnot efficiency. Here, the authors use finite-size-scaling theory to investigate whether this ultimate limit can be achieved at finite power using quantum Otto
Michele Campisi, Rosario Fazio
doaj +1 more source
There is limited understanding of how patella realignment or patellectomy to surgically manage patellofemoral pain (PFP) affects knee biomechanics. By analysing marsupials like kangaroos that lack an ossified patella, actionable biomimetic insight for ...
Manaal Fatima +3 more
doaj +1 more source

