A new family of diverse skin peptides from the microhylid frog genus phrynomantis [PDF]
, 2020 A wide range of frogs produce skin poisons composed of bioactive peptides for defence against pathogens, parasites and predators. While several frog families have been thoroughly screened for skin-secreted peptides, others, like the Microhylidae, have ...
Ballet, Steven +7 more
core +1 more source
Motivated proteins: a web application for studying small three-dimensional protein motifs [PDF]
, 2009 <b>BACKGROUND:</b> Small loop-shaped motifs are common constituents of the three-dimensional structure of proteins. Typically they comprise between three and seven amino acid residues, and are defined by a combination of dihedral angles and ...
A Herráez +23 more
core +4 more sources
Frog foams and natural protein surfactants [PDF]
, 2017 Foams and surfactants are relatively rare in biology because of their potential to harm cell membranes and other delicate tissues. However, in recent work we have identified and characterized a number of natural surfactant proteins found in the foam ...
Cooper, Alan +3 more
core +1 more source
Structure- and context-based analysis of the GxGYxYP family reveals a new putative class of glycoside hydrolase. [PDF]
, 2014 BackgroundGut microbiome metagenomics has revealed many protein families and domains found largely or exclusively in that environment. Proteins containing the GxGYxYP domain are over-represented in the gut microbiota, and are found in Polysaccharide ...
Chang, Yuanyuan +5 more
core +2 more sources
The structure of latherin, a surfactant allergen protein from horse sweat and saliva [PDF]
, 2013 Latherin is a highly surface-active allergen protein found in the sweat and saliva of horses and other equids. Its surfactant activity is intrinsic to the protein in its native form, and is manifest without associated lipids or glycosylation.
Alan Cooper +6 more
core +1 more source
Predicting the conformations of peptides and proteins in early evolution. A review article submitted to Biology Direct [PDF]
, 2008 Considering that short, mainly heterochiral, polypeptides with a high glycine content are expected to have played a prominent role in evolution at the earliest stage of life before nucleic acids were available, we review recent knowledge about ...
Milner-White, E.J., Russell, M.
core +4 more sources
VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase [PDF]
, 2014 BACKGROUND: FAF1 is a ubiquitin-binding adaptor for the p97 ATPase and belongs to the UBA-UBX family of p97 cofactors. p97 converts the energy derived from ATP hydrolysis into conformational changes of the p97 hexamer, which allows the dissociation of ...
Alexandru, Gabriela +7 more
core +4 more sources
The genomes of two key bumblebee species with primitive eusocial organization [PDF]
, 2015 Background: The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies.
Amdam, Gro V. +143 more
core +16 more sources
Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]
, 2014 Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
A Berry +61 more
core +3 more sources
Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™. [PDF]
, 2013 Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma.
Dykstra, Andrew B +2 more
core +2 more sources