Results 21 to 30 of about 26,946 (162)
Advanced Healthcare Materials, EarlyView.Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel +13 more
wiley +1 more source
Nucleic Acids Research, 2005 The RNA-binding ability of ribosomal protein L1 is of profound interest since the protein has a dual function as a ribosomal protein binding rRNA and as a translational repressor binding its mRNA.
N. Nevskaya +9 more
semanticscholar +1 more source
SUMO1 hinders α‐Synuclein fibrillation by inducing structural compaction
Protein Science, 2023 Small Ubiquitin‐like Modifier 1 (SUMO1) is an essential protein for many cellular functions, including regulation, signaling, etc., achieved by a process known as SUMOylation, which involves covalent attachment of SUMO1 to target proteins.
R. Panigrahi +4 more
semanticscholar +1 more source
Advanced Materials, EarlyView.Biological and biologically‐inspired functional nanostructures with structural, thermal, optical, and sensing applications are reviewed. The role of nanoscale features in biological materials on performance is described, and their blueprints are used for bio‐inspired nanomaterials, synthesized using advanced techniques (i.e., photolithography, bio ...
Chao Hsuan (Joseph) Sung +15 more
wiley +1 more source
Protein Science, 2022 Enteric microbial pathogenesis, remarkably a complex process, is achieved by virulence factors encoded by genes located within regions of the bacterial genome termed pathogenicity islands. Salmonella pathogenicity islands (SPI) encodes proteins, that are
S. Ray +8 more
semanticscholar +1 more source
Advanced Science, EarlyView.Researchers discovered that fibronectin fibers lose their tension in specific areas of glioblastoma brain tumors, accumulating in the lumen of proliferating blood vessels and in parenchyma next to infiltrating immune cell clusters. A novel molecular tension probe enables the mapping of fibronectin's fiber tension in glioblastoma for the first time ...
Michele Crestani +6 more
wiley +1 more source
I-Ad-binding peptides derived from unrelated protein antigens share a common structural motif.
Journal of Immunology, 1988 Purified Ia molecules can specifically bind many unrelated peptide Ag, and such binding appears to be a necessary, albeit not sufficient, prerequisite for the immunogenicity of the proteins from which such peptides are derived.
Alessandro Sette +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.Nrf2 isn't just a protector—it's a driver of cancer stemness. The study uncovers how arsenic‐activated Nrf2 directly upregulates KLF4, a key pluripotency factor, fueling oncogenic reprogramming. Through enhancer activation and self‐reinforcing loop, Nrf2 and KLF4 co‐opt gene networks linked to epithelial‐to‐mesenchymal transition and tumor growth ...
Ziwei Wang +9 more
wiley +1 more source
Advanced Science, EarlyView.FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou +8 more
wiley +1 more source
Advanced Science, EarlyView.This figure is a candidate for the cover image. It shows a whole‐mount fluorescent image of lymphatic vessels (red) in the heart of an adult Cdh5‐Dre; Prox1‐RSR‐CreER; Rosa26‐tdT mouse. Image courtesy of Ximeng Han. Abstract Cell fate determination is a fundamental process in multicellular development.
Hui Chen +3 more
wiley +1 more source