Results 31 to 40 of about 6,129 (164)

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Characterization and phylogenetic analysis of the chitinase gene from the Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus [PDF]

, 2004
A putative chitinase gene was identified within the fragment EcoRI-K of the Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus (HearNPV, also called HaSNPIV) genome.
Arif, BM, Chen, XW, Deng, F, Hu, ZH, Hu, ZH, Chinese Acad Sci, Wuhan Inst Virol, Joint Lab Invertebrate Virol, Wuhan 430071, Peoples R China, Jehle, JA, Lauzon, H, Peng, HY, Wang, HL, Wu, D   +9 more
core   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

First-principle molecular dynamics with ultrasoft pseudopotentials: parallel implementation and application to extended bio-inorganic system

, 2003
We present a plane-wave ultrasoft pseudopotential implementation of first-principle molecular dynamics, which is well suited to model large molecular systems containing transition metal centers.
Car, R., De Angelis, F., Giannozzi, P.
core   +1 more source

The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization [PDF]

, 2018
Bacterial peptidoglycan glycosyltransferases (PGT) catalyse the essential polymerization of lipid II into linear glycan chains required for peptidoglycan biosynthesis.
Dowson, Christopher G., Khalid, Syma, Lloyd, Adrian J., Punekar, Avinash S., Roper, David I., Samsudin, Firdaus, Scott, David J.   +6 more
core   +3 more sources

NIR Light‐Driven Photocatalytic Antibacterial Hydrogels for Synergistic MRSA Biofilm Eradication and Wound Regeneration

Advanced Science, EarlyView.
The nanohybrid hydrogel (Fe‐BOS@C/H Gel) is composed of Fe‐Bi2O2‐XS (Fe‐BOS) photocatalysts and CS‐ADH/OHA (C/H) hydrogel. Fe‐BOS photocatalysts achieve near‐infrared (NIR) light‐driven antibacterial photocatalytic/mild photothermal therapy (APCT/MPTT), effectively eliminating methicillin‐resistant Staphylococcus aureus (MRSA) biofilms. The degradation
Dong Mo, Yujia Wei, Meng Pan, Wen Chen, Yun Yang, Kang Li, Xicheng Li, Jianan Li, Qingya Liu, Hanzi Deng, Mei Zhu, Zhenpeng Zhang, Zhaolin Xiao, Zhiyong Qian   +13 more
wiley   +1 more source

Structural Influence of gene networks on their inference: Analysis of C3NET [PDF]

, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Altay, Gokmen, Emmert-Streib, Frank
core   +3 more sources

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Adaptive plasticity of killifish (Fundulus heteroclitus) embryos: dehydration-stimulated development and differential aquaporin-3 expression [PDF]

, 2009
13 pages, 7 figures, 3 tablesEmbryos of the marine killifish Fundulus heteroclitus are adapted to survive aerially. However, it is unknown if they are able to control development under dehydration conditions.
A Esteban, A Esteban, AH Morris, AM Cheung, AP Wheeler, AP Wheeler, BM Tang, C Guerin, C Guerin, C Richard, C Stoll, D Annane, Deutsche Gesellschaft für Anästhesiologie und Intensivmedizin, DG Ashbaugh, DK Heyland, DR Dantzker, E Troncy, ER Pacht, GJ Peek, GR Bernard, GU Meduri, H Gerlach, HP Wiedemann, J Mancebo, JE Gadek, K Lewandowski, K Lewandowski, KP Steinberg, L Gattinoni, L Gattinoni, L Gattinoni, L Gattinoni, L Gattinoni, LB Ware, M Confalonieri, P Pelosi, P Singer, P Taccone, PE Marik, R Kopp, R Rossaint, R Rossaint, RO Hopkins, RP Dellinger, RP Dellinger, RP Dellinger, RW Taylor, S Grasso, S Grasso, S Lundin, T Bein, WM Zapol, Y Sakr   +52 more
core   +1 more source