Results 51 to 60 of about 5,716 (123)
Non-coding RNAs in Transcriptional Regulation [PDF]
, 2015 Transcriptional gene silencing guided by small RNAs is a process conserved from protozoa to mammals. Small RNAs loaded into Argonaute family proteins direct repressive histone modifications or DNA cytosine methylation to homologous regions of the genome.
Aravin, Alexei A., Chen, Yung-Chia Ariel
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The FEBS Journal, EarlyView.Cystathionine β‐synthase (CBS) is an essential enzyme involved in cysteine metabolism. The mutation R336C, associated with severe homocystinuria and of high incidence in Qatar, reduces its activity. Our research shows that this mutation does not destabilize the enzyme fold but subtly alters the tautomeric equilibrium of the PLP cofactor within the ...
Carolina Conter +10 more
wiley +1 more source
Edible bird's nest (EBN) is a potential natural product against influenza virus infection [PDF]
, 2017 Edible bird’s nest (EBN) is an emergent industry in Malaysia. In 2016, EBN worth RM 1.2 billion with the total production of 228-tonne metrics. EBN is salivary secretion of swiftlets (Aerodramus spp.) that contained various nutritive values. Back in Tang
Abdul Razak, Intan Shameha +3 more
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The FEBS Journal, EarlyView.Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický +22 more
wiley +1 more source
Biocentric Work in the Anthropocene: How Actors Regenerate Degenerated Natural Commons
Journal of Management Studies, EarlyView.Abstract As natural commons vital to selves, organizations, and institutions collapse under cumulative anthropogenic pressures, can human agency still reverse some of the damage already done? This article explores how emerging forms of social symbolic work regenerate degenerated natural commons.
Laura Albareda, Oana Branzei
wiley +1 more source
A Chromosome Inversion Creates a Supergene for Sex and Colour in Lake Malawi Cichlids
Molecular Ecology, EarlyView.ABSTRACT Cichlid fishes have the highest rates of evolutionary turnover of sex chromosomes among vertebrates. Many large structural polymorphisms in the radiation of cichlids in Lake Malawi are associated with sex chromosomes and may also carry adaptive variation.
Kristen A. Behrens +10 more
wiley +1 more source
Genomic structure and transcriptional regulation of grass carp calmodulin gene [PDF]
, 2009 A fish calmodulin (CaM) gene was characterized for the first time in grass carp. The CaM gene is about 12-Kb in size with identical intron/exon organization as that of mammalian CaM genes.
Huo, L, Wong, AOL
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Factors determining chromosomal localization of transposable elements in plants
Plant Biology, EarlyView.We review transposon chromosomal niches, and the functional consequences of their specific chromosomal localization in plants. Abstract Transposable elements (TEs) constitute a significant part of plant genomes and shape their genomic landscape. While some TEs are ubiquitously dispersed, other elements specifically occupy discrete genomic loci.
E. Kejnovsky +3 more
wiley +1 more source
TLR-9 Expression in Human Bronchial Epithelial Cells induced with Lipopolysaccharide [PDF]
, 2010 The study conducted here was to investigate the gene and protein expression of Toll like receptor 9 when human bronchial epithelial cells were induced by lipopolysaccharide.
Sangeetha Dharmalingam +1 more
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On the satisfaction of backbone-carbonyl lone pairs of electrons in protein structures [PDF]
, 2016 Protein structures are stabilized by a variety of noncovalent interactions (NCIs), including the hydrophobic effect, hydrogen bonds, electrostatic forces and van der Waals’ interactions.
Afzal +57 more
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