Results 81 to 90 of about 6,129 (164)

Stimuli‐Responsive Chemical Systems That Mimic Biological Dynamics

open access: yesChemistry – A European Journal, Volume 32, Issue 1, 2 January 2026.
Chemists are designing synthetic systems that mimic life's dynamic behaviors, such as motion, sensing, adaptation, and compartmentalization, by integrating reaction networks with stimuli like light, pH, and chemical fuels. This mini‐review surveys molecular machines, responsive materials, nucleic acid networks, and artificial cells, highlighting how ...
Antonio Aguanell   +3 more
wiley   +1 more source

Recycling of Thermoplastics with Machine Learning: A Review

open access: yesAdvanced Functional Materials, Volume 36, Issue 3, 8 January 2026.
This review shows how machine learning is revolutionizing mechanical, chemical, and biological pathways, overcoming traditional challenges and optimizing sorting, efficiency, and quality. It provides a detailed analysis of effective feature engineering strategies and establishes a forward‐looking research agenda for a truly circular thermoplastic ...
Rodrigo Q. Albuquerque   +5 more
wiley   +1 more source

HTGTS‐TCR‐Seq for Profiling of Mouse and Human T‐Cell Receptor α and β Gene Rearrangements and Diversity

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
HTGTS‐TCR‐seq is an efficient and cost‐effective method for profiling TCRα and TCRβ rearrangements using only a few primers. It captures both productive and nonproductive recombination events, minimizes primer bias, and reveals stage‐specific and age‐related repertoire changes in mice, as well as conserved features in human peripheral T cells ...
Rui Luo   +9 more
wiley   +1 more source

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang   +14 more
wiley   +1 more source

A Pan‐TE Map Reveals the Important Role of Transposable Elements in Gene Expression and Phenotypic Diversity in 2,311 Rapeseed Accessions

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
This study presents the first pan‐transposable element (TE) atlas in rapeseed, profiling over 8 million TEs across 2311 accessions. Integrative analyses reveal that TEs broadly shape gene expression through diverse regulatory mechanisms, with key insertions in BnaA03.FLC and BnaA09.CYP78A9 linked to flowering time and silique development.
Zhiquan Yang   +9 more
wiley   +1 more source

Leveraging 3D Molecular Spatial Visual Information and Multi‐Perspective Representations for Drug Discovery

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
A deep learning framework called MolVisGNN is proposed to fuse 3D molecular visual information of drugs with multi‐source features, which proves the importance of 3D molecular visual information of drugs and the advancedness of this model in the field of drug discovery, and provides a reference for how to more comprehensively express small molecule ...
Zimai Zhang   +9 more
wiley   +1 more source

Convergent evolution of plant and animal embryo defenses by hyperstable non-digestible storage proteins [PDF]

open access: yes, 2017
Fil: Pasquevich, María Yanina. Universidad Nacional de La Plata. Instituto de Investigaciones Bioquímicas de La Plata; ArgentinaFil: Dreon, Marcos Sebastián. Universidad Nacional de La Plata.
Dreon, Marcos Sebastián   +4 more
core  

RNF39 promotes colorectal cancer progression by driving RINT1 degradation and suppressing ER stress‐induced apoptosis

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
RNF39, an E3 ubiquitin ligase upregulated by MEF2D in COAD, promotes RINT1 degradation, affecting UPR and ER stress. Loss of RNF39 leads to RINT1 accumulation, enhancing CHOP expression and sensitizing cells to apoptosis. Abstract Background Colorectal adenocarcinoma (COAD) cells exploit stress‐adaptation programs, such as the unfolded protein response
Lu Chen   +7 more
wiley   +1 more source

Integrating Morphology and Chloroplast Genomics: A New East Asian Species of Aletris (Nartheciaceae) With Insights Into Regional Phylogeny and Evolution

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
Based on morphological and chloroplast phylogenomic analyses, we describe Aletris medogensis as a new species endemic to the eastern Himalayas. Comparative genomics revealed structural variations, hypervariable markers, and signatures of positive selection in key genes, providing robust evidence for species delimitation and insights into the ...
Xiong Li   +5 more
wiley   +1 more source

The First Complete Chloroplast Genome of Lycium shawii: Genomic Architecture, Molecular Phylogenetics and Evolutionary Insights

open access: yesEcology and Evolution, Volume 16, Issue 1, January 2026.
The study presents the first complete chloroplast genome of Lycium shawii (PQ824997.1) spanning 155,936 bp and contains 128 genes (84 protein‐coding genes, 36 tRNAs, and eight rRNAs). Nucleotide diversity analysis highlighted atpI, rbcL, and accD as hypervariable loci suitable for DNA barcoding. Molecular dating analysis revealed that L.
Manal Mohammed Ahmed Asiri   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy