Results 201 to 210 of about 28,347 (262)

Developmental Scarcity Induces Sex Differences in Social Recognition and CA2 Perineuronal Nets. [PDF]

open access: yeseNeuro
Waters RC   +5 more
europepmc   +1 more source

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang   +11 more
wiley   +1 more source

Bio‐Inspired Gradient Heterogeneous Architectures for Ultrasensitive and Robust Strain Sensors via Programmable Crack Engineering

open access: yesAdvanced Science, EarlyView.
Inspired by the insect campaniform sensillum, a heterogeneous bilayer strain sensor is developed based on a unique impedance mismatch and three‐dimensional structural dynamic percolation strategy. The sensor enables real‐time multi‐joint teleoperation of three joints and the gripper using a six‐degree‐of‐freedom robotic‐arm platform.
Qi Wu   +4 more
wiley   +1 more source

Non‐Coding Transcripts From Diversified Members of IgLec Family Protect Antiviral Effectors From Viral miRNA

open access: yesAdvanced Science, EarlyView.
The IgLec gene family generates both protein‐coding antiviral effectors and non‐coding transcripts. Upon viral infection, non‐coding transcripts are preferentially targeted by viral miR‐N48, thereby buffering protein‐coding isoforms from repression. Depletion of these decoy transcripts compromises antiviral defense, revealing a non‐coding RNA‐mediated ...
Ying Huang   +5 more
wiley   +1 more source

LLMs as Representation Generators for Gradient‐Free Scientific Optimization: A Case Study in Battery Fast Charging

open access: yesAdvanced Science, EarlyView.
Large language models serve as representation generators for gradient‐free scientific optimization. Two complementary approaches produce executable battery‐charging policies either directly or through LLM‐designed neural representations coupled to Bayesian optimization.
Ge Lei   +3 more
wiley   +1 more source

Trait Dataset for 3,000 European Wild Bee and Hoverfly Species. [PDF]

open access: yesSci Data
Miličić M   +43 more
europepmc   +1 more source

A Generalizable Multimodal Model for Treatment‐Stratified Risk and Survival Assessment under Real‐World Constraints: A Multi‐Center Study of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
DAIMS is a multimodal model for treatment stratified risk and survival assessment in colorectal cancer. Training draws on pathology, genomics, and clinical reports, yet inference requires only whole slide images, and adaptation to new cohorts proceeds without target survival outcomes.
Chuangjie Cao   +15 more
wiley   +1 more source

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